Donders Institute for Brain, Cognition and Behaviour
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Theme 2: Perception, Action and Control

Predictive Brain

Prediction and AttentionPerception and decision-making are not automatic processes, but strongly shaped by internal brain states, which incorporate our goals, attention, expectations, and knowledge about the world.

The mechanisms by which these “top-down factors” affect perception, cognition, and behavior are still largely unknown. Where do the neuronal top-down signals come from? How do they change communication between sensory and decision-related brain regions? And how do these factors affect our perception and decision-making? These questions are the focus of investigation of our group. We use a combination of behavioural and neuroimaging methods (MEG, fMRI, TMS) in healthy volunteers to examine how percepts and decisions are shaped by what we expect (prediction) and deem relevant (attention).

Contact
Name: Floris de Lange
Telephone: 024-3610658
Email: floris.delange@donders.ru.nl
Fax: 024-3610989
Visiting address: Donders Centre for Cognitive Neuroimaging
Kapittelweg 29
6525 EN Nijmegen
The Netherlands
Postal address: Donders Centre for Cognitive Neuroimaging
P.O. Box 9101
6500 HB Nijmegen
The Netherlands
Key grants and prizes
  • Heineken Young Scientist Award for Cognitive Science 2012 (Royal Dutch Academy of Sciences, KNAW)
  • Biomag Young Investigator Award 2012 (Biomag Organization)
  • Open Competition Grant (Netherlands Science Foundation, NWO-MaGW) 2011
  • VENI Grant (Netherlands Science Foundation, NWO-MaGW) 2009
  • Rubicon Grant (Netherlands Science Foundation, NWO-MaGW) 2007
Key publications
  • de Lange FP, Rahnev D, Donner TH, Lau HC (2013). Pre-stimulus oscillatory activity over motor cortex reflects perceptual expectations. Journal of Neuroscience, in press
  • de Lange FP, van Gaal S, Lamme VA, Dehaene S (2011). How awareness changes the relative weights of evidence during human decision making. PLoS Biology, 9(11): e1001203. pdf
  • Kok P, Jehee JFM, de Lange FP (2012). Less is more: Expectation sharpens representations in the primary visual cortex. Neuron 75, 265-270. pdf
  • Kok P, Rahnev D, Jehee J, Lau HC, de Lange FP (2012). Attention reverses the effect of prediction in silencing sensory signals. Cerebral Cortex 22, 2197-2206. pdf
  • Todorovic A, de Lange FP (2012). Repetition Suppression and Expectation Suppression Are Dissociable in Time in Early Auditory Evoked Fields. Journal of Neuroscience, 32, 13389-95. pdf

Links

Predictive Brain lab