Donders Institute for Brain, Cognition and Behaviour
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Theme 4: Brain Networks and Neuronal Communication

Neuroinformatics

Donders Institute for Brain, Cognition and BehaviourThe Tiesinga group in the Neuroinformatics department currently has three research themes. First, to understand processing of sensory information in the brain, and the modulation thereof by cognitive factors, at the level of networks of spiking neurons. This is accomplished by building biophysical models ranging in size from single neurons up to many hundred thousands of neurons.

Second, to develop methods to analyze multivariate data recorded from the brain in order to quantify communication between cortical networks. This is accomplished by determining robust ways of determining the Granger causality and applying information theoretical approaches. Third, to test theoretical hypotheses at the cortical microcircuit level by recording from cultures.

Within the department, Dr. Francesco Battaglia uses a systems neuroscience approach to study how the interaction between brain areas subserves memory and other cognitive processes.

Contact
Name: Paul Tiesinga
Telephone: 024-3652232
Email: paul.tiesinga@donders.ru.nl
Visiting address: Department of Neuroinformatics
Faculty of Science
Heyendaalseweg 135
6525 AJ Nijmegen
The Netherlands
Postal address: Department of Neuroinformatics
Faculty of Science
P.O. Box 9010
Internal mailbox 66
6500 GL Nijmegen
The Netherlands
Key grants and prizes
  • Neuroseeker FET IP
  • Human Brain Project FET Flagship
  • eScience project Biomarker Boosting (NWO)
Key publications
  • Memmesheimer, R.M. & Timme, M. (2012) Non-additive coupling enables propagation of synchronous spiking activity in purely random networks. PLoS Comput Biol, 8, e1002384
  • Toups, J.V., Fellous, J.M., Thomas, P.J., Sejnowski, T.J. & Tiesinga, P.H. (2012) Multiple spike time patterns occur at bifurcation points of membrane potential dynamics. PLoS Comput Biol, 8, e1002615
  • Tiesinga, P.H. (2012) Motifs in health and disease: the promise of circuit interrogation by optogenetics. Eur J Neurosci, 36, 2260-2272
  • Memmesheimer, R.M. (2010) Quantitative prediction of intermittent high-frequency oscillations in neural networks with supralinear dendritic interactions. Proc Natl Acad Sci U S A, 107, 11092-11097
  • P.H.E. Tiesinga and T.J. Sejnowski, Cortical Enlightenment: Are Attentional Gamma Oscillations Driven by ING or PING? Neuron 63 (2009) 727-732

Link
http://www.ru.nl/neuroinformatics/


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Theme 4:
Neural Computation and Neurotechnology

Donders
Research Group
Neuroinformatics

Principal Investigator
Prof. dr. Paul Tiesinga

Special appointments
Dr. Mike Cohen
Prof.dr. Simon Fisher

Group members:

Professor
Dr. Francesco Battaglia

Associate Professor
Dr. Martin Vinck

Assistant Professor
Dr. med Lisa Genzel (M.D.)

Postdocs
Dr.ir. Rembrandt Bakker
Nestor Timonidis

PhD-students
Francesca Abela
Charl Linssen
Nestor Timonidis
Meron Vermaas
Marije ter Wal
Xiaochen Zhao

PhD students (PI: Francesco Battaglia)
Morgane Audrain
Alejandra Alonso
Matteo Guardamagna
Esther Holleman
Rafael Pedrosa
Tim Schroder

Postdocs (PI: Francesco Battaglia)
Melisa Maidana Capitan
Arne Meijer
Federico Stella
Bryan Souza
Karola Kaefer 
Davide Spalla
Arie Kim

Senior researchers (PI: Francesco Battaglia)
Jeroen Bos
Ronny Eichler

PhD student (PI: Lisa Genzel)
Anumita Samanta

Postdocs (PI: Lisa Genzel)
Jacqueline van der Meij

Junior researcher (PI: Lisa Genzel)
Adrian Aleman Zapata

Lab Manager (PI: Lisa Genzel)
Liz van den Brand

(update May 2022)