The translational neuroscience unit (TNU) is the animal research unit of the Donders Institute. Across labs our research covers basic neuroscience - Memory, Sleep, Development, Stress - as well as disease related studies, such as stress-related disorders such as PTSD, depression, anxiety and developmental disorders.
TNU researchers also work with alternative methods, such as fruitflies, organoids, computer models and human experiments with imaging, and are regularly involved in outreach activities explaining the need for animal usage in research as well as communicating the results obtained in animal research.
The TNU strives for openness in animal research and is also an EARA member. In June 2021, Radboud University has also signed the transparency agreement where signatories commit to be open and transparent about using animals in research. To celebrate this, in May 2022 an open day was held at the TNU. An impression of that event can be found here.
Facility & methods
Within the TNU over 80 researchers, coordinated by two staff members. Our research uses inbred and outbred mice and rats. We make use of alternatives as much as possible. At our disposal are mazes, prep rooms and object recognition rooms and many more research methods and facilities.
At the Donders Institute both fundamental and (bio-)medical research is performed in a wide range of neuroscientific fields. At present, not all research questions can be answered by laboratory research or research with human volunteers. Therefore, research is also conducted with animals.
Researchers & results
Several researchers of the Donders Institute make use of the TNU facilities. This resulted in a broad range of publications and running experiments. Our research output improves knowledge and treatment in diverse fields, from stress and memory to ALS and visual impairment.