Antimicrobial resistance in neonates and children in humanitarian situations

Monday 26 September 2022, 10:30
PhD defence
Connecting the dots: challenges and solutions for antimicrobial resistance in neonates and children in humanitarian settings
Speaker or Ph. D. student
A.D. Lenglet MSc.
Promotor(s)
prof. dr. H.F.L. Wertheim
Co-promotor(s)
dr. J. Hopman
Organisation
Faculty of Medical Sciences
Location
Aula

Antimicrobial resistance is an acute and growing global health problem. In humanitarian settings, where infectious diseases tend to flourish (due to broken down public health systems, overcrowding, etc.), AMR is therefore also a concern. Neonates and children represent the largest proportion of patients seen by humanitarian healthcare facilities. This research described the burden of AMR in vulnerable neonates admitted to a neonatal care unit in Port au Prince, Haiti, and children presenting for care with suspected bloodstream infections in Anka, Nigeria. We showed that bacteria with high levels antibiotic resistance were causing infections in both settings, leading to substantial mortality.  The research also showed that improving access to microbiological diagnostics and simple tools to improve antibiotic stewardship, outbreak detection and hand hygiene adherence are part of the solution to tackle AMR in humanitarian settings.

Annick Lenglet has worked since 2006 as an infectious disease epidemiologist in different countries and contexts. She started her PhD studies around antimicrobial resistance in neonates and children in humanitarian situations in 2018 with Médecins Sans Frontières and the Medical Microbiology Department of Radboudumc. She currently works as an Antimicrobial Resistance Advisor at the International Centre for Antimicrobial Resistance Solutions (ICARS) in Copenhagen.

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