Psoriasis is a common skin disease accompanied by redness and scaliness of the skin. Patients with severe psoriasis can typically be treated effectively with biologics; these are recurring injections to suppress the psoriasis. Biologics are effective, but costly. This thesis demonstrates that good results can be achieved with the newest biologics, but also that patients still have substantial treatment goals after achieving good control over their psoriasis. Furthermore it remains important to screen patients for joint complaints (psoriatic arthritis) because these can develop even in patients with few skin complaints. Also, dermatologists in the Netherlands and worldwide are striving to lower standard doses in patients that have effectively controlled psoriasis, in order to find the minimal-but-effective dosage. The goal of this is to reduce side effects and medication-related costs. The insights from this thesis will contribute to further improving the care for patients with psoriasis using biologics.
Marloes van Muijen (1993) graduated from the medical study programme at Radboud University in Nijmegen in 2018. Following this, she started her PhD research in the Department of Dermatology at Radboudumc. She is now a student of dermatology at Maastricht UMC+.