CT video of knee movement: Applications in knee replacement and kneecap instability

Thursday 9 July 2026, 10:30 am
Dynamic CT for in vivo knee kinematics: Applications in total knee arthroplasty and patellofemoral instability
PhD candidate
M.R. Boot
Promotor(s)
prof. dr. E.J.M. Tanck, dr. D.W. Janssen
Co-promotor(s)
dr. S.A.W. van de Groes
Location
Aula

Knee pathologies such as osteoarthritis and patellofemoral instability are complex and difficult to fully understand with traditional static scans, as these do not show knee movement. This research demonstrates dynamic CT can provide new insights into this. It shows that healthy knees typically rotate around the inner side of the joint, while knees with osteoarthritis more often exhibit altered rotation patterns and greater displacement of the medial side, which may indicate reduced stability. In addition, small but consistent changes in motion were observed after knee replacement surgery compared to preoperatively. The research also showed that length changes of virtual ligament fibers during movement depend on the attachment point, which may be relevant for graft placement and preventing complications. These insights may contribute to more accurate diagnostics and better-informed surgical planning. Meanwhile, dynamic CT is used to a limited extent, and further research is needed to better establish its clinical value.

Miriam Boot (1996) obtained her Master's degree in Biomedical Engineering from Eindhoven University of Technology in 2021. Subsequently, she started her PhD research at the Orthopaedic Research Laboratory of Radboudumc.