Exploring the Complex Regulation of Our Biological Processes: Insights into Hemostasis and Inflammation Using Omics Layers.

Monday 8 May 2023, 10:30 am
PhD student
N. Vadaq drs.
prof. dr. A.J.A.M. van der Ven, prof. dr. M.H. Gasem
dr. Q. de Mast, dr. V. Matzaraki

This study has shown that using different omics layer to study biological processes can help us learn more about how our bodies work, especially when it comes to hemostasis/blood clotting system and inflammation. The research also highlights the importance of studying people from different ethnic backgrounds, as both genetics and environment factors can determine our health status. Particularly, our study found that a traditional diet can have a more positive effect on blood clotting system and inflammation than a Western-style diet, which is important for people in both Sub-Saharan Africa and industrialized societies. This study also looked at people living with HIV (PLHIV) who are taking medication for a long time and found a particular subset of people who may be at higher risk for certain diseases. This highlights the need for more personalized healthcare to prevent comorbidities in PLHIV.

Nadira Vadaq (1993) obtained her medical degree, cum laude, at the Gadjah Mada University, Indonesia in 2017 after which she worked as an emergency and primary health care doctor in Lombok, Indonesia. In 2018 she started with her PhD research as part of the Department of Internal Medicine of Radboudumc. Currently, she is working as the post-doctoral researcher in the 2000HIV project, Department of Internal Medicine of Radboudumc.