Infections with nontuberculous mycobacteria (NTM) are rare and because of that a lot about these infections is unknown and methods to identify them need to be improved. Important unknown topics are how often they occur, why treating them is so difficult, how the human body influences treatment and how we can best recognize them. Within this thesis the number of people with NTM infections in 6 European countries including The Netherlands and in Japan was determined. In addition, the way these bacteria survive antibiotic treatment and the effect of human cells on this treatment is studied. Finally, a new, more detailed, method to recognize these infections is tested and introduced for use in the hospital.
Jodie Schildkraut (1993) obtained her Master's degree in Biomedical Sciences, cum laude, at the Radboud University in 2017. In 2017 she then started with her PhD research as part of the Mycobacteriology Group within the Department of Medical Microbiology of Radboudumc. Currently, she is working as the Clinical Project Manager for the UNITE4TB consortium within the Radboudumc.