This study examined how interference fit and surface properties affect the stability of cementless knee implants. Comparing two fit levels (350 µm and 700 µm) showed no significant improvement in stability with higher interference. However, greater fit caused more bone deformation without enhancing fixation. Rougher coatings produced higher friction, increasing mechanical interaction at the interface. Physiological loading revealed that implant stability varies regionally and depends on joint forces during activities such as walking and squatting. Overall, excessive interference fit provides no mechanical advantage and may increase bone stress. These findings highlight the importance of individualized surgical strategies tailored to bone quality and patient factors to improve implant longevity and clinical outcomes in cementless total knee arthroplasty.
Esther Sánchez, from Monterrey, Mexico, holds B.Sc. and M.Sc. degrees in Biomedical Engineering (ITESM, TU/e). She researched implant fixation at Radboudumc, publishing five peer reviewed articles during her PhD. Transitioning into Clinical Regulatory Affairs, she was a consultant and now serves as Regulatory Affairs Specialist, managing global medical device compliance, strategy, and clinical evaluations.