Seminar: Enzyme Motors and Pumps: From Transport to Collective Behavior

Monday 8 July 2024, 11 am

One of the more interesting recent discoveries has been the ability of enzymes to catalytically harness the chemical energy in their environment for mechanical work. Recent work from our group has shown that enzymes participating in catalytic cascades show surprising emergent behavior, ranging from directional chemotactic motility in response to chemical gradients to dynamic assembly driven by phoretic effects. The resultant organization and collective behavior of interacting active enzymes show remarkable similarities to the biological world. When enzymes are anchored to surfaces, the catalytic reactions can propel the fluid. We will show that precise sculpting of fluid flow including flow enhancement and flow reversal becomes possible in coupled pump systems depending on the geometric placement of the pumps. In essence, the layout of the activated enzyme-attached patches forms an “instruction set” that guides the flowing solution to specific sites in the system. These studies provide a new route for forming self-organizing flow systems that can yield fundamental insights into non-equilibrium, dynamical systems.

prof. Ayusman Sen (USA)
When
Monday 8 July 2024, 11 am
Speaker
Prof. Ayusman Sen - Dept. of Chemistry, Pennsylvania State University (USA)
Locations
Huygens building, HG00.303