EPAN: Experimental Psychopathology and Affective Neuroscience

In this research group, we study how emotions and psychological processes contribute to anxiety and stress-related disorders. We focus on understanding the control over motivation, particularly in approach-avoidance behaviours. By examining acute emotional reactions and their impact on decision-making, we aim to improve early detection and intervention for psychopathological conditions.


In our research, we use neurocognitive techniques, like brain imaging methods (fMRI, MEG, and EEG), to investigate defensive stress reactions, along with neural stimulation techniques (TMS, tACS, and TUS), as well as pharmacological interventions involving steroid hormones. We study healthy individuals, clinical populations with anxiety and stress-related disorders, and professionals at risk, such as police officers. We utilise emotional control and decision-making tasks, and our assessments encompass psychophysiological measures such as heart rate, SCR, pupil dilation, and behavioural changes.

Research projects

Decision Under Stress Training (DUST)

In this project, we train police officers to control their stress physiology in engagingly provoking situations with a Virtual Reality biofeedback game

Nijmegen longitudinal study

The NLS has been following children since 1998 to examine the influence of parent and peer interactions on their development. This includes looking at interactions with temperament and personality traits at different ages.


We contribute our knowledge to:

Bachelor's programmes in

Research Master's programmes in

Contact information


Maria Montessori building

Thomas Van Aquinostraat 4
6525GD Nijmegen
Postal address
Postbus 9104