MR Structural Quantitative Imaging

Structural magnetic resonance imaging can give you beautiful images of the brain… but do they don’t tell us much about the tissue properties of a given brain region.

Our group focuses on creating new strategies to obtain both high quality and informative images that take full advantage of the interaction of the used magnetic fields (static and radiofrequency) with the tissues electro-magnetic tissue properties.

This is done by: developing new sequences for in vivo imaging free artifacts, developing biophysical tissue models and strategies to transform the obtained imaging data into quantitative tissue information.

We contribute to the understanding of the mechanisms that give rise to the observed relaxation and devise protocols that could give clinicians and neuroscientists an increased capability to measure tissue property maturation, degeneration and viability. And because we like our subjects to enjoy their scanning sessions, we would like to do this as fast as possible!

Key grants and prizes

  • 2019-2022 Metabolic Anatomic and Physiologic MRI Endogenously- Health Holland
  • 2017-2021 Thinking Inside the Voxel – what can magnetic fields tell us about brain white matter properties NWOi –FOM
  • 2015-2017 Advanced high-field MR imaging and quantitative analysis for segmentation of the thalamic nuclei -Swiss National Foundation
  • 2011-2015 Susceptibility Mapping of the Human Brain – Swiss National Foundation

Key publications

Research Group
MR Structural Quantitative Imaging

Principal Investigator

José P. Marques

Group members


Renaud Hedouin

PhD candidates

Xinjie Chen – PhD student co-supervised in Basel, Switzerland

Rocio Artigas – PhD Student co-supervised in Santiago, Chile

Master students

Marianke Rinner – Master Student


Contact information

Postal address
Postbus 9101