While structural magnetic resonance imaging (MRI) provides stunning images of the brain, it often reveals little about the underlying tissue properties of specific brain regions. Our research group is dedicated to bridging this gap by developing advanced strategies that transform high-quality imaging into meaningful, quantitative data.
We aim to leverage the interaction between magnetic fields (both static and radiofrequency) and the electromagnetic properties of tissues to enhance the information obtained from MRI scans. Our work focuses on three key areas:
- Development of new sequences for in vivo quantitative imaging, with reduced biases & artifacts (and as fast as possible!);
- Development of biophysical tissue models that can be used to decode an interpret tissue properties;
- Creating strategies to transform imaging data into quantitative metrics that are consistent and comparable across different subjects, scanners and platforms
Through our research, we contribute to the understanding of the mechanisms that give rise to the observed relaxation, allowing us to give clinicians and neuroscientists tools to measure tissue maturation and degeneration throughout the lifespan, in both health and disease.