Analytical Chemistry & Chemometrics

Department

The department of Analytical Chemistry & Chemometrics consists of the Analytical Chemistry & Chemometrics research group (AC&C) and the Life Science Trace Detection Laboratory (TDLab). The AC&C research group focuses on chemometrics. This is the discipline within chemistry that develops methods to extract relevant information from chemical data. This ranges from simple localisation of data to prediction of, for instance, concentrations or finding biologically interesting molecules in complex mixtures. Research of the TDLab focuses on experimental methods for reliable detection and quantification of volatile compounds in complex gas mixtures. The department is part of Institute of Molecules and Materials (IMM).

Below are the highlights of the Analytical Chemistry & Chemometrics group. View all News, Publications, Projects, Staff, and Vacancies.

Highlights

Research of TDLab featured in National Geographic

05 March 2025 Research news item

The research of the Life Science Trace Detection Laboratory (TDLab), part of the Institute for Molecules and Materials (IMM) at Radboud University has been featured in the latest issue of National Geographic.

Letters NWO met een trofee icoon in het midden

NWA Innovative grants for research on Redox Flow batteries and Novel solutions for mapping individual exposure

08 January 2025 Research news item

Researchers Evan Zhao and Simona Cristescu from IMM have been awarded two NWA Innovative grants for the projects Multimodal measurement platform for energy-dense Redox Flow batteries and Novel Solution Towards Mapping the Individual Exposure.

NWA-ORC grant project ExpACT: Exposome ACTions perspectives for a healthy air quality environment

08 November 2024 Research news item

TDLab is part of a consortium that has received a grant within the NWA-ORC programme. The focus of the project is on an increased exposure of citizens to potentially harmful air emissions of emerging chemical and biological substances.

Analytical Chemistry & Chemometrics

Research of the Analytical Chemistry & Chemometrics group is centered around two main research philosophies.

Methodological Chemometrics

(Further) development of chemometric methods to tackle new challenges in chemistry and beyond: methodological research on chemometrical techniques like global optimisation methods, and multivariate statistics.

Application Oriented Research

These chemometric methods are applied and validated for pioneering science in chemistry and biology. This encompasses for instance image processing and spectroscopic analysis (NIR, LC-MS/MS) for industrial and medical applications.

Publications

Life Science Trace Detection Laboratory

Research in the Trace Detection Laboratory (TDLab) focuses on reliable detection and quantification of volatile compounds in complex gas mixtures. TDLab develops and applies techniques and analytical methodologies using state-of-the-art laser-based spectroscopy and mass spectrometry for a wide range of gas concentrations.

Applications in Life Science Areas

Biomarkers detection
Monitoring for precision medicine, fruit storage and dairy farming
Air pollution monitoring, plasma diagnostics

More information about TD Lab

Breath analysis

Internships

Both research groups AC&C and TDLab offer various Bachelor's and Master's courses, incidental courses and Bachelor's and Master's internships. Would you like to do your internship at our department? Please view the list of internship subjects and get brigitte.loozen [at] ru.nl (in touch) for more information. A few examples of relevant subjects are:

Multispecies open-path molecular absorption spectroscopy
Algorithm Development for Faraday Tomography: Bridging Data Science and Astrophysics
Exploring NIR-HSI and Machine Learning for Quality Control in Electronic Components
Anomaly Detection in HSI Using Data Inner Polygon
Modelling of emission fluxes from spectroscopic data
In-situ spectroscopy of plasmas