Attention to unmet needs in inflammatory bowel diseases: Exploring the potential of mindfulness-based cognitive therapy

Monday 9 November 2026, 2:30 pm
PhD candidate
M.M. ter Avest
Promotor(s)
prof. dr. A.E.M. Speckens, prof. dr. G. Dijkstra
Co-promotor(s)
dr. L.H.C. Nissen, dr. M.J. Huijbers
Location
Aula

Patients with inflammatory bowel disease (IBD) frequently experience psychological symptoms, fatigue, and sleep problems in addition to physical symptoms, with a substantial impact on their quality of life. This thesis investigated the healthcare needs of patients with IBD and the potential of mindfulness-based cognitive therapy (MBCT). The first part of this thesis demonstrates that the factors contributing to impaired quality of life differ according to age and sex. Younger patients more frequently experience mental health problems, whereas physical functioning plays a more prominent role in older patients. In addition, women generally report a lower quality of life. Among patients with severe fatigue, the severity and impact of fatigue, perceptions about fatigue, and the role of healthcare professionals influence whether patients seek help for these symptoms. Patients also emphasize the importance of holistic, patient-centered care. The second part of this thesis demonstrates that MBCT may be a valuable treatment option for reducing symptoms of anxiety and depression in this patient population. In addition, MBCT may have beneficial effects on fatigue, sleep, and disease activity. MBCT also appears to be a feasible intervention, with peer support, the option to participate online, and personal commitment facilitating participation, while the required time commitment and the impact of the disease may act as barriers. In conclusion, the findings of this thesis underscore the importance of person-centered IBD care that addresses physical, psychological, and social concerns. MBCT may provide an effective and feasible adjunctive treatment option within this approach.