TNU
TNU

Translational Neuroscience Unit (TNU)

The translational neuroscience unit (TNU) is the animal research unit of the Donders Institute. The unit is located within the Animal Research Facility (CDL) of Radboudumc and comprises an interdisciplinary team. All researchers at the TNU will use alternatives to animal research as much as possible.

Fundamental and (bio-)medical research

In the Donders Institute both fundamental and (bio-)medical research is performed. At present, not all research questions can be answered by laboratory research or research with human volunteers. Therefore, research is also conducted with animals. All researchers at the TNU will use alternatives to animal research as much as possible. Our researchers use organoids (Kolk lab), simpler animal models such as flies (Storkebaum lab), computer models (Englitz lab, and others) and humans themselves (Genzel lab, Homberg lab). At the TNU we make use of a large maze, object recognition rooms, prep rooms and many more techniques. Across labs our research covers basic neuroscience - Memory, Sleep, Development, Stress - as well as disease related studies, such as stress-related disorders such as PTSD, depression, anxiety and developmental disorders. For more information on the general need for animals in research please see the general information on research with animals.

Lisa Genzel

TNU Researchers

Several researchers of the Donders Institute make use of the TNU facilities.

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TNU

Examples of techniques

HExMaze, surgeries, object recognition paradigm, contextual fear conditioning and other techniques

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DM1-2

DM1-2

Biosafety level 1 and 2 rooms (DM1 and 2) to do experiments involving the use of viruses.

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Mouse used in a research setting, standing on a small instrument

General information on research with animals

Discover how Radboud University approaches this and why animal research remains essential.

/en/about-us/policies-and-regulations/animal-research

Governance

The TNU is governed by the TNU board, which is comprised of four senior researchers of the TNU with a term of at least 2 years and meets monthly. The TNU board chair and co-chair switch every 2-years between Radboud and RadboudUMC. The TNU board is advised by the TNU user group, that is comprised of PhD and PostDocs and meets twice a year. To reach the TNU board please email tnucoordinators.cns [at] radboudumc.nl (tnucoordinators[dot]cns[at]radboudumc[dot]nl).

All experiments are approved and supervised by the members of the Animal Welfare Body. Thus all research is performed and supervised by a diverse group of people, independently checking for animal welfare as well as research quality.

Contact TNU

Feel to contact us for questions about your research.

Visiting address

TNU
Geert Grooteplein 29
6525 EZ Nijmegen
The Netherlands

+31(0)24 11111