Preclinical Drug Discovery
Preclinical Drug Discovery

Introduction to Preclinical Drug Discovery - Registration no longer possible

Join this unique course organized by Radboud University, Pivot Park Life Science Campus, and HAN, and dive into the key aspects of today’s drug discovery process. Guided by leading experts from academia and industry, you’ll explore the latest technologies, challenges, and opportunities in pharmaceutical R&D. Through a dynamic mix of lectures, seminars, and hands-on assignments, you’ll gain valuable insights into how molecules are transformed into life-changing medicines.
Location: Pivot Park in the city Oss (30 KM off campus)

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    General

    Registration no longer possible

    The course will be organized jointly by Radboud University (Nijmegen), Pivot Park Life Science campus (Oss) and HAN University of Applied Sciences (Nijmegen), covering the most important aspects of modern drug discovery. A selection of the following subjects will be covered during the course: 

    • Principles and challenges of drug discovery
    • Different phases of drug discovery
    • Conventional and novel therapeutic modalities
    • Target identification and validation
    • Assay development and  hit finding through high-throughput screening
    • Importance of hit triaging and validation of target engagement
    • Medicinal chemistry and hit & lead optimization
    • ADMET, animal PoC
    • Chemistry Manufacturing and Controls
    • Regulatory affairs
    • IP generation and
    • Clinical studies

    The content of the lectures are designed by academic and industry experts in the field of early drug discovery and the course is a combination of lectures, seminars, group assignments and visits to companies active in pharmaceutical R&D located on Pivot Park Life Science Campus. The course is EFMC certified.

    Learning objectives

    After this course, you will:

    1. Understand how drugs are discovered and developed
    2. Understand in general terms the process of drug discovery
    3. Understand the basic principles of medicinal chemistry
    4. Understand the important factors for a molecule to become a drug

    Please note that this course is taught on Pivot Park in the city of Oss (30KM off campus).

    Collaborating partners

    logos partners

    Starting date

    30 June 2025, 8:30 am
    City
    Oss
    Costs
    €888
    Discount
    15% when applying before 1 April 2025
    VAT-free
    Yes
    Educational method
    On-site
    Main Language
    English
    Deadline registration
    15 May 2025, 11:59 pm
    Maximum number of participants
    35

    Factsheet

    Type of education
    Summerschool
    Entry requirements
    The applicants should have a Bachelor in any of the molecular sciences (chemistry, molecular life sciences, biology, physics) or a related program.
    Study load (ECTS)
    2
    Result
    Certificate, Edubadge
    Organisation
    Radboudumc

    Contact information

    Radboud Summer School
    Postbus 9102
    6500 HC NIJMEGEN

    radboudsummerschool [at] ru.nl (radboudsummerschool[at]ru[dot]nl)

    Week 2:
     

    Start date: Monday the 30th of June 
     

    End date: Friday the 4th of July

    Location: Pivot Park in the city Oss (30 KM off campus)

    program_2025.docx

    Floris Rutjes

    Prof. Floris Rutjes received his PhD at the University of Amsterdam in 1993 under the supervision of the late Prof. Speckamp. After a post-doctoral stay with Prof. Nicolaou at The Scripps Research Institute (La Jolla, USA) and an assistant-professorship at the University of Amsterdam, he became full professor in organic synthesis at Radboud University (Nijmegen, NL) in 1999. His research interests comprise the synthesis of biologically active heterocyclic molecules, the development of new bioorthogonal click-probes for chemical ligation, and continuous flow synthesis in microreactors. He has received several awards including the Gold Medal of the Royal Netherlands Chemical Society (2002) and the AstraZeneca Award for Research in Organic Chemistry (2003). He is co-founder of several companies and in 2008 received the award of ‘Most entrepreneurial scientist of the Netherlands 2008’. Currently, he is Director of the Institute for Molecules and Materials at Radboud University and President of the European Chemical Society (EuChemS).

    Pedro Hermkens looking at camera

    Pedro Hermkens (PhD) has a scientific background in organic chemistry, pharmacology and biochemistry. He worked at Organon, Schering-Plough and MSD (Merck) in the Medicinal Chemistry Department for 21 years where he was responsible for projects in several therapeutic areas as team leader. Furthermore, he has experience in the early stage of the process as Discovery Leader. In this role he was responsible for managing target identification & validation, assay development, screening & hit identification & optimization. In 2013 he became director of the Institute Applied BioSciences & Chemistry of the HAN University of Applied Sciences. In this position he was responsible for education and research of this institute. In 2020 he accepted the position of lector Drug Discovery at the HAN University of Applied Sciences.

    Dennis Lowik looking at camera

    Dr. Dennis Löwik earned his MSc in Organic Chemistry from the University of Nijmegen in 1994 and his PhD in Medicinal Chemistry in 1998 under the guidance of Prof. Rob Liskamp at Utrecht University. He then undertook a postdoctoral fellowship in Cambridge, UK, in the biotechnology group of Prof. Chris Lowe until 2000. This was followed by a year in the Supramolecular Chemistry group of Prof. Bert Meijer at TU Eindhoven. In 2001, he joined the Bio-organic Chemistry group at Radboud University Nijmegen, where he has held an associate position since 2006. His research focuses on smart materials and targeted drug delivery systems. Since 2024, next to his work at the Radboud University he is also lector Drug Discovery at HAN University of Applied Sciences. In addition, he is a co-founder and advisor at Aurelius Therapeutics.

    Joost Uitdehaag looking at camera

    Joost Uitdehaag is an accomplished expert in oncology drug discovery. He transformed preclinical concepts into more than a dozen clinical candidates and had an insider's perspective on the discovery and development of the blockbuster drug acalabrutinib and world's best selling cancer drug pembrolizumab. He has plenty of drug discovery experience both in industry and academia. As Head of Biology at Crossfire Oncology, he is currently developing effective degrader-antibody conjugates . Before that, he worked at AstraZeneca where he chaired the global committee for scouting and validating new targets in haematology. As founding member of the biotech company NTRC, he was instrumental in bringing the TTK/PLK1 inhibitor BAL-0891 to clinical phase. He got his Ph.D. at the university of Groningen and was a EMBO post doc at the university of Oxford. He is the author of >130 publications and co-author on >5 patents, h-index 31. He regularly gives lectures on drug target validation for a.o. HAN, Avans and Radboud University and has written a biomedical thriller set in the world of drug discovery.

    Costs

    Early bird | €754,80

    The deadline for our early bird application is 31 March 2025.

    Regular | €888

    The deadline for our regular application is the 15 May 2025.

    Includes

    Your course, coffee and tea during breaks, warm lunch every day, welcome dinner on Monday, Official Opening, Official Closing.

    Excludes

    Transport, accommodation, social events and other costs. 

    Discounts and scholarships

    There are discounts and scholarships available for our partners. Click below to find out if you are eligible. 

    Discounts and scholarships

    Admission

    Level of participant

    Master

    Admission requirements

    Applicants should have a Bachelor in any of the molecular sciences (chemistry, molecular life sciences, biology, physics) or a related program.

    Admission documents

    Motivation letter.