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The course will be organized jointly by Radboud University (Nijmegen), Pivot Park Life Science campus (Oss) and HAN University of Applied Sciences (Nijmegen), covering the most important aspects of modern drug discovery. A selection of the following subjects will be covered during the course:
- Principles and challenges of drug discovery
- Different phases of drug discovery
- Conventional and novel therapeutic modalities
- Target identification and validation
- Assay development and hit finding through high-throughput screening
- Importance of hit triaging and validation of target engagement
- Medicinal chemistry and hit & lead optimization
- ADMET, animal PoC
- Chemistry Manufacturing and Controls
- Regulatory affairs
- IP generation and
- Clinical studies
The content of the lectures are designed by academic and industry experts in the field of early drug discovery and the course is a combination of lectures, seminars, group assignments and visits to companies active in pharmaceutical R&D located on Pivot Park Life Science Campus. The course is EFMC certified.
Learning objectives
After this course, you will:
- Understand how drugs are discovered and developed
- Understand in general terms the process of drug discovery
- Understand the basic principles of medicinal chemistry
- Understand the important factors for a molecule to become a drug
Please note that this course is taught on Pivot Park in the city of Oss (30KM off campus).