About our research
This Master’s specialisation is tightly connected to the Radboud Institute for Molecular Life Sciences (RIMLS), a leading research institute at the interface of the Radboud university medical center and the Faculty of Science. On this page, you can read more about the relevant research institute(s) and departments in which our highly renowned research takes place.
Radboud Institute for Molecular Life Sciences
The Radboud Institute for Molecular Life Sciences is a leading interfaculty research institute of the Faculty of Science (Radboud University) and of the Faculty of Medical Sciences (Radboudumc). Integrating the
scientific expertise of both molecular and medical sciences, RIMLS aims to achieve a greater understanding of the molecular mechanisms of disease. Research areas from RIMLS- Faculty of Science include epigenetics, stem cell and developmental biology, and bioinformatics.
The research in the field of Epigenomics is organised in two departments at Radboud University: Molecular Biology and Molecular Developmental Biology. Both departments are part of RIMLS. You’ll perform your first internship in one of these departments, or a related department. The second internship can also take place at a medical department, another university in the Netherlands or abroad or at a related company.
The Molecular Biology department focuses on genetic and epigenetic pathways in health and disease. Sometimes they zoom in on one specific protein, but often the research encompasses genome and proteome wide elucidation of complete molecular mechanisms. This includes the analysis of transcription factor binding, 3D structures, epigenetic marks, DNA-methylation, RNA transcriptomes and epigenetic reader complexes. With both next-generation sequencing techniques and state-of-the-art quantitative mass-spectrometry genomics, epigenomics and proteomics are combined in one cellular approach.
Molecular Developmental Biology
A central theme in the research of the department of Molecular Developmental Biology is developmental gene regulation. They work on questions like: Which genes play a role in cell development? What is the role of epigenetic mutations in their transcription? And how can we use bioinformatics to study interactions between DNA and proteins? The answers lead to an extended knowledge on pluripotency, cell lineage commitment and various diseases.