About our research
Research institutes
The Master’s specialisation in Medicinal Chemistry is closely linked to several research departments within the Institute for Molecules and Materials (IMM), in close collaboration with the Radboud Institute for Molecular Life Sciences (RIMLS). We stimulate you to become an independent researcher, under the guidance of more experienced researchers in the lab. During your Master's internship you’ll get access to all relevant research facilities and laboratories in the Huygens building and also to radiographic instruments in the academic hospital Radboudumc, located just across the road.
Institute for Molecules and Materials
IMM is an interdisciplinary research institute in chemistry and physics. The mission of IMM is to perform fundamental research to understand, design, and control the functioning of molecules and materials.
Institute for Molecules and Materials
Radboud Institute of Molecular Life Sciences
RIMLS does research within the domain of molecular mechanisms of disease and particularly in the fields of cell biology, molecular medicine, and translational research.
Research groups
During your Master's, you will perform at least one internship at one of our research groups. Relevant groups are:
The group focuses on the development of new and sustainable synthetic (multistep) reactions by using bio-, organo- or metal-catalysts or combinations thereof, synthesis of druglike compound libraries, synthesis of bio-orthogonal click-reactions and chemical synthesis in continuous flow microreactors.
The research carried out in this department is aimed at a better understanding of cellular stress and autoimmunity at the molecular level. Specific molecular features like protein unfolding and aggregation and post-translational modifications play crucial roles in these phenomena.
In nature, countless complex structures are known, and mimicking these structures can be a challenging task. How do you design a nano- or micro-system from the bottom up? Our goal is to design functional supramolecular structures and apply them to advance the field of nanomedicine.
We focus on bridging data-driven artificial intelligence (AI) and physics-based 3D modelling to better understand the molecular basis of health and diseases and to rationalize drug design.
Research facilities
The experimental research facilities at Radboud University and Radboudumc are large scale national and sometimes international multi-user centres. Several facilities offer possibilities for medicine development, clinical validation of biomarkers, therapy development, and the analysis and development of molecules for (nano-)medicines. Possible applications include the use of mass spectrometry, next-generation sequencing and the Nanomedicine Valorisation lab. RIMLS has access to the Central Animal Facility, the Radboud Biobank, Microarray facility Nijmegen, Flow Cytometry, Microscopic Imaging Centre (MIC), Bioluminiscence Imaging, in Vivo Multi-photon Microscopy, a Good manufacturing Practice (GMP) facility and the Radboud Proteomics centre.
Magnetic Resonance Research Center
The focus of the MRRC research center is the development and application of nuclear magnetic resonance (NMR) methods that enable the study of local structure and dynamics in functional materials. Located in the Goudsmit Pavilion, the laboratory houses eight NMR spectrometers for both liquid- and solid-state NMR research up to 850 MHz.
Mass Spectrometry
The Technology Center for Mass Spectrometry offers high-level expertise in bioanalytical mass spectrometry combined with in-depth knowledge on biomedical and clinical applications, embedded in a cutting-edge clinical and fundamental research environment.