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IMM colloquium by prof. Gijsje Koenderink: 'The material properties of soft living matter' (Lecture)

Thursday 22 April 2021Add to my calendar
from 16:00
prof. Gijsje Koenderink (TU Delft)
Preceding lecture
Ceremony for the Best Thesis Awards 2020 by prof. Dave Parker

Gijsje KoenderinkCells and tissues are highly dynamic but at the same time need to withstand large mechanical loads. This paradoxical mechanical behavior is governed by fibrous protein scaffolds known as the cytoskeleton and the extracellular matrix. Fibrous networks have many advantageous mechanical properties: fibers can form space-filling elastic networks at low volume fractions and they reversibly stress-stiffen, which provides protection from damage. However, it is still poorly understood how biopolymer networks can combine these features with the ability to dynamically adapt their structure and mechanics. I will summarize recent insights in this question obtained via quantitative measurements on reconstituted cytoskeletal and extracellular matrix networks. We perform these measurements from the macroscopic scale (using rheology) all the way down to the molecular scale (using optical tweezers, in situ small-angle-X-ray scattering, and atomic force microscopy). I will furthermore mention connections to applications in bottom-up synthetic biology and for tissue (re)generation.

Prof. Koenderink will be available after her talk for further discussions.

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See the announcement sent by  email or contact the organizers.