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Theme 2 colloquium by prof. Elias Vlieg: 'Deracemization of everything? ' (Lecture)

Date
Tuesday 10 March 2020Add to my calendar
Time
from 16:00
Location
HG00.307
Speaker
prof. Elias Vlieg (Solid State Chemistry)
Description

Elias VliegUnderstanding how single-handedness of biological molecules came about has been of interest since Pasteur first separated mirror-image crystals of tartaric acid. It is also highly relevant, since for pharmaceutical applications it is often necessary to produce a chirally pure product, i.e. containing only one of the two possible enantiomers. There are several chiral purification or resolution methods. Here crystallization routes will be discussed that can convert a racemic mixture to 100% chiral purity, with a focus on so-called Viedma ripening and temperature cycling. Our current understanding and our efforts to extend their range of applicability will be discussed.

Contact
Peter Korevaar & Evan Spruijt