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Seminar: "Unraveling post-transcriptional regulatory networks governing rapid adaptive responses in (pathogenic) microorganisms" (Lecture)

Date
Thursday 27 June 2019Add to my calendar
Time
from 12:00
Location
Figdor Lecture Theatre – RIMLS (Research Building Radboudumc), Geert Grooteplein 26-28, Floor 8, Route 289
Speaker
dr. Sander Granneman ( University of Edinburgh, Centre for Synthetic and Systems Biology (SynthSys))
Description

Sander GrannemanWork in my lab is focusing on understanding how microorganisms manage to rapidly adapt to sudden changes in their environment. Many pathogenic species have developed very sophisticated mechanisms to efficiently scavenge essential nutrients from the host environment and even evade the host immune system. Our research is focused on post-transcriptional regulation by small non-coding RNAs and RNA-binding proteins, using Methicillin resistant Staphylococcus aureus as a model system. Key Publications

•Kinetic CRAC uncovers a role for Nab3 in determining gene expression profiles during stress. Nat. Commun.; s41467-017-00025-5, 2017

•Robust statistical modeling improves sensitivity of high-throughput RNA structure probing experiments. Nat. Methods; 14: 83–89, 2017

Contact
prof. Ger Pruijn