Classification of brain tumours
Analytical Chemistry and Radiology, UMC St. Radboud
(2005 - 2006)
MRI (Magnetic Resonance Imaging) and MRS (Magnetic Resonance Spectroscopy) are often used to diagnose and identify brain tumours. However, MR spectra are complex and expertise is required for interpretation. In order to assist radiologists in the diagnosis of tumours, pattern recognition techniques can be used to allow a fast identification of MR spectra. Arjan de Jong has used MR spectra to train Kohonen maps, to distinguish between spectra from healthy tissue and spectra from different tumorous tissue types. This technique may be used in the future to assist radiologists in their interpretation of MR spectra.
Experimental design for microreactors
Analytical Chemistry and Organic Chemistry
March 2007 - ...
Microreactors offer an elegant way to study complex reactions. Because the process is completely automated, a large number of experiments are possible in a short amount of time. In a collaboration between the departments of Analytical Chemistry and Organic Chemistry, Noud van Harskamp investigates the influence of several experimental factors, such as time and stoichiometry. He uses several types of experimental design to identify beforehand the most useful set of experiments to perform. Statistical modelling then leads to chemical insight: not only is it possible to identify the optimal set of conditions, but the coefficients of the equation can also be interpreted in a chemical way.
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