Cursus MED-B3MIN02 Studiepunten (ECTS) 11 Categorie BA (Bachelor) Voertaal Engels Aangeboden door Radboud Universiteit; Faculteit der Medische Wetenschappen; Biomedische wetenschappen; Docenten Contactpersoon van de cursus dr. K. van den Dries Overige cursussen docent Examinator dr. K. van den Dries Overige cursussen docent Collegejaar 2023 Periode MIN-MADI   (04-09-2023 t/m 31-08-2024) Aanvangsblok MIN-MADI Onderwijsvorm voltijd Opmerking - Inschrijven via OSIRIS Ja Inschrijven voor bijvakkers Ja Voorinschrijving Wachtlijst Ja Plaatsingsprocedure Op basis van loting Toelichting Op basis van loting

	Cursusdoelen After completion of the Minor, students are able to: Explain the fundamentals of the major types of imaging modalities, both preclinical and clinical Perform laboratory experiments to prepare samples for different microscopy approaches Explain the basics for operating the major imaging modalities, through hands-on experience  Perform a basic quantitative analysis on images obtained from various imaging modalities Choose the most appropriate imaging modality for a particular preclinical or clinical application Inhoud How can we visualize single molecules in cells? How can we follow the growth and metastasis of tumors? How can we track the migration of immune cells through the body? Imaging in biomedical sciences is vital for research, diagnosis and visualization of health and disease. Rapid technological developments in the imaging field are increasing our capabilities to address important biomedical questions. This Minor provides an in-depth and hands-on introduction to the various imaging modalities used both in preclinical and clinical settings. Going from molecule to man, this Minor will allow the students to understand and operate several key imaging techniques, including those at the molecular/cellular level (e.g. fluorescence and electron microscopy), at the tissue/animal level (immunohistochemistry and intravital imaging) and at the whole-body level (X-ray/CT, ultrasound, MRI and PET/SPECT). In addition, students will practice how to perform a basic analysis on the images generated by these techniques and will get a first glimpse on the application of artificial intelligence for image analysis. During the practical courses, the students will also gain hands-on experience with operating different imaging modalities, as well as basic techniques required for preparation of samples, such as immunolabeling with antibodies. After this Minor, students will be able to design experiments involving imaging, with an understanding of the advantages and disadvantages of each modality. Relation This Minor builds on prior molecular, cell biological, genetic, immunological, and basic imaging knowledge provided in the Bachelor's programs for Biomedical Sciences and Medicine. Key words Fluorescence microscopy, super-resolution microscopy, electron microscopy, sample preparation, histology, in vivo imaging, cell culture, immunofluorescence, X-ray, ultrasound, MRI, CT, PET, SPECT, image analysis. Study path The Minor contains plenary and interactive lectures, practicals, literature study, journal club presentations, the writing of a mini-review (on a self-chosen imaging-related topic), and practical lab work, including report writing.  Examination Assessment consists of five parts (each must be graded at least 5.5 or ‘Pass’ to pass the course): Midterm exam, open questions (Individual; weight 30%) Microscopy assignment, report (Group; weight 10%) Journal club, presentation (Group; weight 10%) Mini-review on medical imaging, presentation and report (Group; weight 20%) Final exam, open questions (Individual; weight 30%) Literature This Minor builds on background information in: ▪ Baynes / Dominiczak: Medical Biochemistry (5th ed., 2019) ▪ Alberts / Hopkin / Johnson / Morgan / Raff / Roberts / Walter: Essential Cell Biology (5th ed., 2019) ▪ Turnpenny PD, Ellard S: Emery's elements of medical genetics (15th ed., 2017) ▪ Parham: The Immune System (4th ed., 2014) Links to additional study material (reviews, primary research papers) will be provided via Brightspace. Remarks Registration, also for resits, has to be done in OSIRIS student.
	Werkvormen Werkgroep Toetsen Mid-term exam (open questions) Weging 30 Toetsvorm Tentamen Gelegenheden Blok MIN-MADI, Blok MIN-MADI Microscopy Assignment (report) Weging 10 Toetsvorm Verslag Gelegenheden Blok MIN-MADI, Blok MIN-MADI Journal Club (presentation) Weging 10 Toetsvorm Presentatie Gelegenheden Blok MIN-MADI, Blok MIN-MADI Mini-review (presentation & report) Weging 20 Toetsvorm Verslag Gelegenheden Blok MIN-MADI, Blok MIN-MADI End-term exam; open questions Weging 30 Toetsvorm Tentamen Gelegenheden Blok MIN-MADI, Blok MIN-MADI