The main objectives of this module are:
After completion of the course, students are able to
- Define the major neural cell types of the nervous system and their proliferation, differentiation and integration in functional neural networks of the CNS.
- Distinguish key molecular signaling pathways critical for learning and memory.
- Explain how disruptions of molecular pathways lead to impaired cognitive performance in neurodevelopmental disorders.
- Understand and explain current methodologies to identify and manipulate neural correlates of learning, memory and behavior.
- Apply such methodologies for dissecting molecular processes related to specific cognitive tasks in a time and cell-specific way.
- Use the newly acquired knowledge to critically evaluate and present a recent manuscript applying these methodologies to study the molecular and cellular mechanisms underlying a neurodevelopmental disorder.
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The module
This course focuses on molecular and cellular processes underlying neural processes in the central nervous system in normal conditions as well as in neural disorders. This module provides comprehensive basic and advanced knowledge of the molecular and cellular biology of neurons and glia, major molecular pathways and mechanisms underlying learning and memory, and the application of state-of-the-art methodologies to identify and manipulate the neural correlates of learning, memory and behavior. The different topics will be discussed in the context of normal functionality and development as well as in pathological aberrations of the nervous system.
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