MED-BMS38
Biomarkers: let's get personal
Cursus informatieRooster
CursusMED-BMS38
Studiepunten (ECTS)3
CategorieMA (Master)
VoertaalEngels
Aangeboden doorRadboud Universiteit; Faculteit der Medische Wetenschappen; Biomedische wetenschappen;
Docenten
Examinator
prof. dr. A.J. van Gool
Overige cursussen docent
Docent
prof. dr. A.J. van Gool
Overige cursussen docent
Contactpersoon van de cursus
prof. dr. A.J. van Gool
Overige cursussen docent
Docent
dr. R. Tans
Overige cursussen docent
Collegejaar2018
Periode
2  (01-10-2018 t/m 25-08-2019)
Aanvangsblok
2
Onderwijsvorm
voltijd
OpmerkingPeriode 2b, donderdag en vrijdag
Inschrijven via OSIRISJa
Inschrijven voor bijvakkersJa
VoorinschrijvingJa
Voorinschrijving geopendvanaf 01-04-2018 t/m 03-09-2018
WachtlijstJa
PlaatsingsprocedureHandmatig door Administratie
ToelichtingHandmatig door Administratie
Cursusdoelen
After completing of the course, students are able to
  1. Define the added value of molecular biomarkers in modern life sciences
  2. Explain the various steps in biomarker discovery  and development
  3. Define the strength and pitfalls in biomarker research
  4. Select the proper omics technology to address a given translational biomarker need
  5. Explain the analytical basis of next generation sequencing and mass spectrometry
  6. Perform basic analysis of next generation sequencing and mass spectrometry data
  7. Design a X-omics study to identify and validate translational biomarkers
Inhoud
This course focusses on molecular biomarkers that drive personalized healthcare and the use of omics technologies for biomarker identification and validation. 
Following the landmark first map of a human genome, the field of molecular life sciences has seen multiple major breakthroughs. Detailed insights in molecular pathways, mechanism-based personalized diagnostics and personalized therapies have changed the way we practice medicine. These are enabled by our better grasp of the molecular building blocks of life: genes and their transcription, protein function and their interaction, and the complex dynamic networks of metabolites. The fields studying these building blocks, i.e. genomics, proteomics and metabolomics (collectively called omics), have seen great technological advances in recent years, resulting in increased throughput, higher accuracy and lower costs of measurements. The huge molecular complexity of human systems cannot be addressed through any of these omics technologies alone. Exciting recent developments show that it has now become technologically feasible to approach molecular biology from different omics angles simultaneously, fueling the new approach of X-omics for biomarker research.

Key words
Biomarkers, Genomics, Proteomics, Metabolomics, personalized diagnostics.
 
Niveau
master

Werkvormen
Werkgroep

Opmerking
Periode 2b, donderdag en vrijdag

Toetsen
Written exam; study proposal
Weging80
GelegenhedenBlok 2, Blok 2

Presentaties
Weging20
GelegenhedenBlok 2, Blok 2