MED-BMS66
Reproductive Toxicology and Epidemiology
Course infoSchedule
Course moduleMED-BMS66
Credits (ECTS)3
CategoryMA (Master)
Language of instructionEnglish
Offered byRadboud University; Faculty of Medical Sciences; Biomedische wetenschappen;
Lecturer(s)
Contactperson for the course
dr. ir. C.J.A. Roeleveld
Other course modules lecturer
Examiner
dr. ir. C.J.A. Roeleveld
Other course modules lecturer
Academic year2017
Period
3  (30/10/2017 to 26/08/2018)
Starting block
3
Course mode
full-time
RemarksPeriod 3b, Thursday and Friday
Registration using OSIRISYes
Course open to students from other facultiesYes
Pre-registrationYes
Pre-registration openfrom 01/04/2017 up to and including 02/10/2017
Waiting listYes
Placement procedureDone manually by Back Office
ExplanationDone manually by Back Office
Aims
The main objectives of this module are:
 
After completion of the course, students are able to:
  1. Define the general principles of reproductive epidemiology and toxicology
  2. Explain the mechanisms of action involved in reproductive toxicity and teratogenicity
  3. Make an informed choice between animal experiments and alternative test methods
  4. Apply advanced methods in reproductive and perinatal epidemiology
  5. Distinguish the most important risk factors for adverse reproductive outcomes
  6. Explain the importance of the placenta in reproductive toxicity
  7. Evaluate and/or design reproductive epidemiologic and/or toxicologic studies
Content
The module 

This course encompasses the fields of reproductive epidemiology and toxicology, covering the entire spectrum from fertility and subfertility through pregnancy complications to adverse perinatal outcomes (e.g. preterm birth and low birth weight) and birth defects in offspring, as a result of exposure to non-genetic risk factors and gene-environment interaction.
 
After a general introduction into the topic, the first week is focused on reproductive toxicology and teratology with emphasis on mechanisms, animal experiments, and alternative test methods. The second week is dedicated to advanced methods in reproductive and perinatal epidemiology, which may differ from epidemiologic methods used to study other disorders. In addition, the main risk factors for adverse outcomes, such as medical and recreational drug use, nutrition, lifestyle and environmental factors, are addressed.
 
In weeks 3 and 4 of the course, you will have the opportunity to apply the knowledge and insights acquired during the first weeks in a small group (2-3 students) assignment and a summative test (60% of grade) in week 4. The topics of the group assignments will be personalized, depending on the background and interests of the students and their primary focus on epidemiology or toxicology. The presentations and discussions of the group assignments on the last day of the course will serve as a test moment (40% of grade) and as a possibility to disseminate the group results to the other course participants and the teachers.
 
Levels
master

Instructional modes
Working group

Remark
Period 3b, Thursday and Friday

Tests
Course examination
Test weight1
OpportunitiesBlock 3, Block 3