Cell migration in health and disease
Cursus informatieRooster
Studiepunten (ECTS)2
CategorieB2 (Tweede jaar bachelor)
Aangeboden doorRadboud Universiteit; Faculteit der Medische Wetenschappen; Geneeskunde;
dr. K.A. Wolf
Overige cursussen docent
dr. K.A. Wolf
Overige cursussen docent
Contactpersoon van de cursus
dr. K.A. Wolf
Overige cursussen docent
VKO-SEM1  (05-09-2022 t/m 05-02-2023)
OpmerkingDoelgroep GNK - BMW - THK
K2: vrijdagochtend
Inschrijven via OSIRISJa
Inschrijven voor bijvakkersNee
PlaatsingsprocedureOp basis van loting
ToelichtingOp basis van loting
In this module the student will:

1. Repeat basis knowledge of ‘Cells in Tissue’ obtained in the Q2 Nature module
    ‘Van Cel naar Weefsel’
2. Learn about processes where migration plays a role in physiology and pathology
3. Learn about the molecular basis of cell migration
4. Be introduced to the basics of cell culture
5. Get acquainted to different types of experimental models applicable to study cell migration
6. Inspect/ perform a small migration experiment
7. Analyze and quantify cell migration parameters from movies (Fiji practical; facultative)
8. Practice to (critically) read and report about a publication from the cell migration field
9. Overall, receive a theoretical and experimental introduction to the field of cell migration.
Cell migration is a fundamental physiological process during embryonic development, immune response and wound healing of the human body. The intrinsic capacity of normally resident adult tissue cells to migrate upon activation can be “mis-used” in certain diseases, for example in cancer, where cell motility can contribute to cancer metastases and mortality.
This course will start with a repetition and question/ answer hour from the ‘Van cell naar weefsels’ part of the Q2 Nature module. This module has offered basic cell biological knowledge on how a  healthy cell, alone or in the tissue context, is built, how it looks  under the microscope, and what are its main functions. Continuing from there, the students will learn about the molecular basis of cell migration and how cell movement is linked to physiologic as well as deregulated migration. A small overview of therapy approaches will be given. Students will be offered lectures and E-learning, will do a small hands-on part, perform data analysis, and will present in a journal club.
The motivation to offer this elective lies in the desire to make students in the biomedical field better understand how cell migration contributes to physiological processes but also underlies disease mechanisms.
This module fits particularly well to BMW students, because it contains a small experimental part. Medical and dental students are welcome as well, but need to be aware of the (in part) molecular character of this elective, as well as be ready to learn tools for scientific work (journal club, lab practicum, data analysis). Medical students that are aware of this focus have enjoyed previous course editions.
Required prior knowledge
The here offered Q6 module will deal with the dynamic aspect of a (cancer) cell. Participation in this module will deepen and broaden, and thus form an excellent extension of, already acquired knowledge on the topics of cell biology, and on cancer. Particularly well-suited preparation courses are the a) Q2 MGZ modules (2MGC, 2MGX, 2MCB, 2MCW), which have offered basic cell biological knowledge on how a healthy cell, alone or in a tissue context, is built, how it functions molecularly, and how it looks like at microscopic resolution; and b) the Q5 module on cancer development (MG7).
Module opzet  / tijdschema
Course language will be English.
55 study hours (10 weeks á 5.5 hours. 1 hour means 45 min+15 min break):
18 contact hours (1/3 of the hours), 35 self study hours (2/3 of the hours), 2 hours exam

GelegenhedenBlok VKO-SEM1, Blok VKO-SEM2