MED-MIN11
Clinical research: principles and practice
Cursus informatieRooster
CursusMED-MIN11
Studiepunten (ECTS)12
CategorieBA (Bachelor)
VoertaalEngels
Aangeboden doorRadboud Universiteit; Faculteit der Medische Wetenschappen; Biomedische wetenschappen;
Docenten
Examinator
dr. ir. F. de Vegt
Overige cursussen docent
Docent
dr. ir. F. de Vegt
Overige cursussen docent
Contactpersoon van de cursus
dr. ir. F. de Vegt
Overige cursussen docent
Collegejaar2018
Periode
K1  (03-09-2018 t/m 25-08-2019)
Aanvangsblok
K1
Onderwijsvorm
voltijd
Opmerking-
Inschrijven via OSIRISJa
Inschrijven voor bijvakkersJa
VoorinschrijvingNee
WachtlijstJa
Plaatsingsprocedure-
Cursusdoelen
Regarding the domains of patient-oriented clinical research, i.e. diagnostic, prognostic and clinical intervention research, the student is able to
  1. stipulate and structure the clinical research question by exploring the corresponding clinical context and by searching and critically appraising the literature
  2. apply the most optimal method of data collection for a given clinical research question, taking validity, accessibility, efficiency and costs into account
  3. discuss the theoretical, practical, ethical and legal aspects of patient based data collection, storage, coding and processing and include these aspects in a clinical study
  4. analyze clinical data transparently, using descriptive and inferential statistical methods, and present and discuss the main results
  5. translate study results into clinical practice anticipating impact, usefulness and cost-effectiveness and communicate with health professionals
Inhoud
Health care is changing fast with constant development of medical technology, either as intervention or diagnostic. Better understanding of the working mechanisms of disease stimulates development of targeted drug therapies. Technical development, such as the use of robotics, may improve health care. And the research in the field of genetics and biomarkers makes personalized health care possible. In clinical practice decisions about the implementation of those new technologies are needed. This are decisions on the level of the patient about the best treatment option in that particular case; decision on the level of the hospital about the purchase of a new Da Vinci Robot (for instance) for surgical procedures; and decisions on macro level in terms of guideline development and reimbursement of care, such as new expensive drugs. These decisions should be made on the basis of the best available evidence.
 
As a Biomedical Science student you are primarily being trained to perform research that can deliver good quality evidence for such decisions. As a physician in training you will be confronted with results from clinical research on a daily basis. This minor is designed to train your skills in clinical research and your scientific attitude in the broadest way. Topics of the minor are:
  • intervention research; designing your own trial
  • data collection; using state of the art applications
  • prediction modeling; first steps in making personalized health care possible
  • journal club; training your critical scientific thinking
  • cost-effectiveness; making decisions from a societal perspective
An important feature of the minor is learning from and being situated in clinical practice. You will perform a clinical research project which is supervised by a medical specialist and a research methodologist. During the minor, in-depth background of clinical research and the research process, explaining the principles and methods used to obtain quantitative evidence are taught. After this minor you will be well equipped to organize, perform and critically appraise clinical research in practice!
 
Key words
Patient-oriented clinical research, diagnostic research, prognostic research, clinical interventions, evidence based medicine (EBM), epidemiology, health technology assessment (HTA)
Niveau
3

Werkvormen
Werkgroep

Toetsen
Research report
Weging40
ToetsvormVerslag
GelegenhedenBlok K1, Blok K1

Research presentation
Weging10
ToetsvormPresentatie
GelegenhedenBlok K1, Blok K1

Written exam; open questions
Weging50
ToetsvormSchriftelijk tentamen
GelegenhedenBlok K1, Blok K1