This course will make you familiar with the clinical appearance of defects in biomolecular interactions and signaling processes that guide growth and development and with the research towards the molecular mechanisms, diagnosis, treatment and prevention of resulting diseases. You will gain knowledge of the various diagnostics for disease classification and of the options for treatment.
After completion of this course you:
- recognize the significance of genomic and transcriptomic profiling technologies in marker discovery and molecular diagnostics of developmental disorders and cancer
- can select appropriate diagnostic testing to provide insight into the molecular basis of hereditary cancers, and translate the results in genetic counseling of patients and family members
- can define the requirements and specificities for the implementation of novel markers in cancer
- understand the principles and potentials of key imaging techniques in translational research, in particular PET and MR and you are able to propose their application in diagnosis.
|
|
|
This course focuses on the translational research associated with the RIMLS research in Genetics, Epigenetics and Nanomedicine, and is scheduled from Friday 14 to Friday 21 October 2016. Together with the preceding course "Cell Growth and Differentiation" (MED-MM3CF) it forms the Module "Cell Growth and Differentiation/Developmental Disorders and Malignancies".
The students will be made familiar with various aspects of translational research in the field of Cell Growth and Differentiation, ranging from molecule to patient care. Current state-of-the-art technologies will be introduced and their application in various inherited and acquired (cancer) disorders, including target gene discovery, gene expression profiling, mutation scans, genomic profiling, (clinical) imaging and bio-informatics, will be dealt with. In addition, applications in (pre-symptomatic) screening and genetic counseling will be reviewed.
|
|