NWI-BB017C
Biochemistry and Molecular Biology II
Cursus informatieRooster
CursusNWI-BB017C
Studiepunten (ECTS)6
CategorieBA (Bachelor)
VoertaalEngels
Aangeboden doorRadboud Universiteit; Faculteit der Natuurwetenschappen, Wiskunde en Informatica; BioWetenschappen;
Docenten
VorigeVolgende 3
Contactpersoon van de cursus
dr. R.C. Bartfai
Overige cursussen docent
Docent
dr. R.C. Bartfai
Overige cursussen docent
Coördinator
prof. dr. A. Cambi
Overige cursussen docent
Docent
dr. C. Logie
Overige cursussen docent
Docent
dr. J.H.A. Martens
Overige cursussen docent
Collegejaar2017
Periode
KW4  (16-04-2018 t/m 02-09-2018)
Aanvangsblok
KW4
Onderwijsvorm
voltijd
Opmerking-
Inschrijven via OSIRISJa
Inschrijven voor bijvakkersJa
VoorinschrijvingNee
WachtlijstNee
Plaatsingsprocedure-
Cursusdoelen

At the end of the course, you can:

  • describe how fundamental molecular processes contribute to the functioning of eukaryotic cells.  (Detailed mechanism of DNA replication, repair, recombination, RNA-synthesis, transcriptional regulation, RNA processing and cell cycle regulation are discussed during the course
  • explain how malfunctioning of the above mentioned mechanisms can contribute to disease and in particular cancer development
  • interpret simple experiments aiming to study the above mentioned processes
  • pinpoint, critically evaluate and present key experiments from recent scientific articles related to the course content
Inhoud

Here, the themes introduced in the first year molecular biology courses for Molecular Sciences and Biology are prolonged and taught in more depth. Focus lies on molecular mechanisms and the molecular means of information flow in eukaryotes, from and to the cell's nucleus. Knowledge acquired in lectures is actively applied in the course by means of tutorials. Furthermore, academic skills such as efficient knowledge acquisition from the primary literature as well as from review articles along with logic and scientific communication are stimulated in the course by preparing and presenting a journal club on a recent Science or Nature paper.

Bijzonderheden
• This course is given in English.
• An adequate assessment of the obligatory oral presentation in the Journal Club is a required part of the course, in addition to the written exam. In order to participate in the Journal Club students have to enroll themselves via Blackboard; if it is not possible for you to use Blackboard, please send a mail to R. Bartfai.
• The textbook Lodish (see above) should be in your possession at the start of the course. If you already have the 7th edition it is not necessary to buy the latest version.

Onderwerpen
• DNA-structure, replication, recombination and repair
• Regulation of transcription of prokaryotes and eukaryotes
• Transcript processing in eukaryotes
• Cell-autonomous control of the cell cycle
• Cancer

Toetsinformatie
• Compulsory participation in Journal Club, assessed at least sufficient
• Written exam

Voorkennis
Students cluster Molecular Sciences: Biomolecules, Biochemical Processes, DNA-technology.Students (medical) Biology: Molecular Biology and Recombinant DNA.

Literatuur

• Lodish et al., Molecular Cell Biology, 7th edition (Publisher: Freeman and company, New York, 2007), ISBN-13: 9781464109812 (should be in your possession at the start of the course)
• Handouts and additonal information distributed via Blackboard

Werkvormen

• 32 hours guided group project work
• 8 hours guided individual project work
• 20 hours lecture
• 4 hours student presentation
• 4 hours question session
• 96 hours individual study period

Verplicht materiaal
Boek
Lodish et al., Molecular Cell Biology, 7th edition (Publisher: Freeman and company, New York, 2007)
ISBN:9781464109812
Blackboard
Handouts and additonal information distributed via Blackboard

Werkvormen
Cursusgebeurtenis

Hoorcollege

Presentatie
AanwezigheidsplichtJa

Project
AanwezigheidsplichtJa

Responsiecollege

Zelfstudie

Toetsen
Tentamen
Weging1
GelegenhedenBlok KW4, Blok KW4