NWI-BB047C
Medical Embryology
Course infoSchedule
Course moduleNWI-BB047C
Credits (ECTS)6
Category02 (Introductory with prior knowledge)
Language of instructionEnglish
Offered byRadboud University; Faculty of Science; BioWetenschappen;
Lecturer(s)
PreviousNext 2
Coordinator
dr. S.M. Kolk
Other course modules lecturer
Examiner
dr. S.M. Kolk
Other course modules lecturer
Contactperson for the course
dr. S.M. Kolk
Other course modules lecturer
Lecturer
dr. S.M. Kolk
Other course modules lecturer
Lecturer
drs. P.R. Matthijsse
Other course modules lecturer
Academic year2019
Period
KW4  (13/04/2020 to 30/08/2020)
Starting block
KW4
Course mode
full-time
Remarks-
Registration using OSIRISYes
Course open to students from other facultiesYes
Pre-registrationNo
Waiting listNo
Placement procedureIn order of application
ExplanationIn order of application
Aims
At the end of the course having followed the (response) lectures and the practical study assignments (obligatory) including Versatest, the student is able to:
  1. understand the basic principles of development and organogenesis in the various animal models including the differentiation of the nervous system, the cardio-vascular system, digestive system and the urogenital system.
  2. recognize and name parts of developing different organ systems.
  3. to set a timing in the consecutive embryonic and fetal developmental stages and recognize the different organ systems in random transversal, sagittal and horizontal sections of the mouse embryo in the different phases of development.
  4. indicate how embryonic appendices will be formed, including the molecules and concepts involved.
Content
The development of a fertilized ovum to a multicellular organism is a remarkable triumph of evolution. During the human embryonic development one cell will divide to millions of cells that together will form complex organ systems. In the last century, the descriptive embryology has given us an overview of the formational changes that an organism needs to go through from its existence till its adulthood. In this century, the human embryology encounters an exciting new era as molecular underpinnings of developmental processes are getting clearer.
This course initially deals with the basal aspects of developmental biology such as the development of the major animal models, description of developmental stages and the fundamental molecular processes in development. Later in the course, the lectures will discuss the early embryonic development of human (formation of the three germ layers, neurulation, and organogenesis), the fetus-mother relationship and the molecular-physiological mechanisms that drive the development of an embryo. Animal models and human organogenesis will be studied by live observations accompanied by assignments in which microscopical slides and illustrations are central. A digital learning environment is created to interactively rehearse and test the course material. In the teratological part of the course disorders are discussed that can appear during embryonic and fetal (mal)development. The demonstrations will be held in the Pathological Museum of the UMC St Radboud, where specimens of human embryos can be studied that have a certain form of misdevelopment.
Level

Presumed foreknowledge
Basic knowledge on Developmental Biology is needed. In the beginning of the course suggestions will be given how to enhance this knowledge. The student has to acquire this knowledge independently and under his/her own responsibility.
Test information
  • exam about the topics dealt with in the lectures, the interactive lectures and the laboratory course, counts for 85%, minimum grade = 5.0
  • exam about topics from the practicals, counts for 15%, minimum grade = 5.0
  • Specifics
    This course will be given in English.This course will be scheduled on Thursdays and Fridays. Several guest lecturers from the hospital will complement the course.
    Additional comments
    This course will be given in English.This course will be scheduled on Thursdays and Fridays. Several guest lecturers from the hospital will complement the course.

    Topics
    • Developmental Biology
    • Human Embryology
    • Teratology

    Test information
    • exam about the topics dealt with in the lectures, the interactive lectures and the laboratory course, counts for 85%, minimum grade = 5.0
    • exam about topics from the practicals, counts for 15%, minimum grade = 5.0

    Prerequisites
    Basic knowledge on Developmental Biology is needed. In the beginning of the course suggestions will be given how to enhance this knowledge. The student has to acquire this knowledge independently and under his/her own responsibility.

    Contact information
    Dr. Sharon M. Kolk, assistant professor
    Department of Molecular Neurobiology
    Donders Centre for Neuroscience (DCN)
    Radboud University
    Geert Grooteplein Zuid 28
    6525 GA Nijmegen
    Email: S.Kolk@donders.ru.nl
    Tel: +31-(0)24-3610565/52580

    Recommended materials
    Book
    Langman's Medical Embryology (with student consult online access), 14th Revised edition - 2018, Wolters-Kluwe International edition, English- Soft cover.
    ISBN:9781975114848

    Instructional modes
    Course occurrence

    Lab course
    Attendance MandatoryYes

    Lecture

    Practical computer training
    Attendance MandatoryYes

    Response course

    Zelfstudie

    Tests
    Exam
    Test weight3
    Test typeDigital exam with Versatest
    OpportunitiesBlock KW4, Block KW4

    Digital Exam
    Test weight17
    Test typeDigital exam with CIRRUS
    OpportunitiesBlock KW4, Block KW4