At the end of the course having followed the (response) lectures and the practical study assignments (obligatory) including Team-Based Learning, the student is able to:
- understand the basic principles of development and organogenesis in the various animal models including the differentiation of the nervous system, the cardio-vascular system, digestive system and the urogenital system.
- recognize and name parts of developing different organ systems using a microscope.
- to set a timing in the consecutive embryonic and fetal developmental stages and recognize the different organ systems in random transversal, sagittal and horizontal sections of the mouse embryo in the different phases of development.
The development of a fertilized ovum to a multicellular organism is a remarkable triumph of evolution. During the human embryonic development one cell will divide to millions of cells that together will form complex organ systems. In the last century, the descriptive embryology has given us an overview of the formational changes that an organism needs to go through from its existence till its adulthood. In this century, the human embryology encounters an exciting new era as molecular underpinnings of developmental processes are getting clearer.
This course initially deals with the basal aspects of developmental biology such as the development of the major animal models, description of developmental stages and the fundamental molecular processes in development. Later in the course, the lectures will discuss the early embryonic development of human (formation of the three germ layers, neurulation, and organogenesis), the fetus-mother relationship and the physiological mechanisms that drive the development of an embryo. Animal models and human organogenesis will be studied by live observations accompanied by assignments in which microscopical slides and illustrations are central. A digital learning environment is created to interactively rehearse and test the course material. In the teratological part of the course, disorders are discussed that can appear during embryonic and fetal (mal)development. There will be an excursion to the Anatomical and Pathological Museum of the Radboudumc, where specimens of human embryos can be studied that have a certain form of maldevelopment.
- Responsive lecture
- Lab sessions
- Team-Based Learning
|Basic knowledge on Developmental Biology is needed. In the beginning of the course suggestions will be given how to enhance this knowledge. The student has to acquire this knowledge independently and under his/her own responsibility.|
| exam about the topics dealt with in the lectures, the interactive lectures and the laboratory course, counts for 85%, minimum grade = 5.0
exam about topics from the practicals, counts for 15%, minimum grade = 5.0|
- The number of participants is maximized, everyone starts on the waiting list, and the education center will enrol the students to the actual course based on Learning Trajectory (2nd years) and on time of enrolment for the other students. This cannot be done before the enrolment deadline for the course has ended, so please make sure to enrol for a back-up course in time!