NWI-BM024D
Course on Laboratory Animal Sciences
Course infoSchedule
Course moduleNWI-BM024D
Credits (ECTS)3
Category03 (Advanced)
Language of instructionEnglish
Offered byRadboud University; Faculty of Science; BioWetenschappen;
Lecturer(s)
PreviousNext 1
Examiner
drs. M.M.J. Kool
Other course modules lecturer
Contactperson for the course
drs. M.M.J. Kool
Other course modules lecturer
Coordinator
drs. M.M.J. Kool
Other course modules lecturer
Lecturer
drs. M.M.J. Kool
Other course modules lecturer
Lecturer
dr. J.A.M. Lorteije
Other course modules lecturer
Academic year2023
Period
KW1  (04/09/2023 to 05/11/2023)
Starting block
KW1/  KW2/  KW3/  KW4
Course mode
full-time
RemarksSee course details for registration.
Registration using OSIRISYes
Course open to students from other facultiesYes
Pre-registrationNo
Waiting listYes
Placement procedureDone manually by Back Office
ExplanationDone manually by Back Office
Aims
Learning objectives course on laboratory animal science
 
 
  1. Is familiar with legislation concerning the use of laboratory animals.
  2. Knows about basic principles, which guide towards the ethical judgement of animal experiments.
  3. Has knowledge of the major anatomical, physiological and ethological characteristics of the commonly used laboratory animal species, with respect to the choice of the proper animal model and insight into possibilities and limitations of biological standardization of laboratory animals.
  4. Has knowledge of the requirements of laboratory animals with respect to housing, nutrition and care with special attention to the enhancement of animal welfare. Has knowledge of hygienic measures and barrier systems and knowledge about safety aspects and health risks when working with laboratory animals.
  5. Possesses the necessary knowledge for responsible animal handling, has knowledge of the different methods for the collection of body fluids and of a number of other often used experimental techniques.
  6. Has knowledge of the impact of diseases in laboratory animals on the experimental approach and knows about health monitoring.
  7. Possesses the knowledge to recognise pain as well as discomfort in laboratory animals.
  8. Has knowledge of the most important methods of anaesthesia, analgesia and euthanasia, which can be used in various laboratory animal species.
  9. Possesses the knowledge to define and apply humane endpoints.
  10. Has insight into the possibilities of alternatives to animal testing.
  11. Knows the possibilities that statistics offer to optimise the use of laboratory animals. Has knowledge of the possible impact of environmental and procedural factors on experimental results and knowledge on quality control. Has knowledge on information systems to search for alternatives; has knowledge of methods of synthesis of evidence like systematic reviews and meta-analysis.
  12. Has knowledge of hygienic measures and barrier systems and knowledge about safety aspects and health risks when working with laboratory animals. has knowledge of the different methods for the collection of body fluids and of a number of other often used experimental techniques. (amongst others injection techniques, oral injection and insertion of catheters).
 
Specific knowledge for mice and rats on items:
  1. Has knowledge of the anatomical and physiological characteristics, breeding, genetics and genetic modification of mice and rats.
  2. Has knowledge of the mice and rats specific methods of handling and procedures.
  3. Has knowledge on the behaviour of mice and rats.
  4. Possesses the necessary knowledge for responsible handling of mice and rats (also obtained some practical experience in this respect).
  5. Pas knowledge of the different methods for the collection of body fluids and of a number of other often used experimental techniques. (amongst others injection techniques, oral injection and insertion of catheters) and obtained some practical experience in this respect.
  6. Possesses the knowledge to recognise symptoms of fear, pain and suffering in mice and rats and to apply human endpoints.
  7. Has knowledge of the mice and rats specific anaesthesia, analgesia and euthanasia methods.
  8. Has knowledge of the requirements of mice and rats with respect to housing, nutrition, care with special attention to the enhancement of animal welfare.
 
Content
The objective of the course on laboratory animal science is to present basic facts and principles that are essential for the humane use and care of laboratory animals and for the quality of research. The course will focus on the responsible and appropriate use of animals in scientific experiments in which alternatives (refinement, reduction, replacement) play an essential role. The course has the aim to gain knowledge and insight into the design of an animal experiment in a scientific and ethically justified manner, taken into account the 3Rs principles.
The program of the course on laboratory animal science comprises the requirements of the Dutch 'Wet op de dierproeven' (Experiments on Animals Act).  The Laboratory Animal Science course includes an introductory course as well as a species-specific course on mice and rats. The certificate of completion of the course together with an academic master degree in biomedical sciences will lead to a legal recognition to design animal experiments in the Netherlands.
The Laboratory Animal Science course referred to in annex 6 belonging to Article 5 of the Ministerial Order on Animal Experiments 2014 (Dierproevenregeling 2014), and meets the requirements referred to in article 23.2(b) and annex V belonging to Article 23.3 of directive 2010/63/EU on the protection of animals used for scientific purposes (22 September 2010) of the European Parliament and of the Council. The course is FELASA accredited for ‘person designing procedures and projects (EU function B; reference 058/17), and will result in a FELASA function B certificate that is valid in all EU countries.

Instructional Modes
  • Lecture
  • Assignments
Level

Presumed foreknowledge
All participants of the course on Laboratory Animal Science will be tested on their knowledge concerning Anatomy/Zoology and Physiology before the start of the course on laboratory animal science. One exception is: Master students who have a BSc degree from Radboud University in (Medical) Biology, Medicine or Biomedical Sciences, do not have to take the knowledge test.This requirement applies for all courses in The Netherlands. Details can be requested at courseinlas.cdl@radboudumc.nl
Test information
  • exam, counts for 75%, minimum grade 5.5
  • group assignment, counts for 25%, minimum grade 6
Specifics
  • The course is an elective in the Master's programmes of (Medical) Biology. The Course on Laboratory Animal Science is organised by the Central Animal Laboratory (CDL) and lectured in English.
  • The course is scheduled in a two weeks full time manner. For dates see the website of the CDL:  https://www.radboudumc.nl/en/education/courses/course-on-laboratory-animal-science-las. The schedule will also be made visible in the persoonlijkrooster.ru.nl if all info is known. 
  • Application should be done by filling out the application form: https://www.radboudumc.nl/en/education/courses/course-on-laboratory-animal-science-las and sent to courseinlas.cdl@radboudumc.nl 
    • FNWI-students should register in OSIRIS as well. They will initially all be placed on a waiting list.
  • Please note there is only place for 30 students. The CDL (courseinlas@radboudumc.nl) will decide who will be registered, based on timely subscription and filled out application form.
  • Requests for further information may also be sent to: courseinlas.cdl@radboudumc.nl.
Required materials
Book
Zutphen, L.F.M. van, Baumans, V. & Beynen, A.C. (eds.), Principles of Laboratory Animal Science: A contribution to the humane use and care of animals and the quality of experimental results, 2001, Elsevier Science Publishers, Amsterdam, 2nd (revised)
Learning Management System (Brigthspace)
A digital module guide will be available. All information about the modules and all course materials for each module are provided in brightspace.

Instructional modes
Course
Attendance MandatoryYes

Lab course
Attendance MandatoryYes

Tests
Exam
Test weight3
Test typeExam
OpportunitiesBlock KW1

Assignment
Test weight1
Test typeAssignment
OpportunitiesBlock KW1