After following this course, you can:
- easily navigate in genomics data; you know where and how to find the data you need
- get up-to-date information about genes of interest
- perform standard bioinformatics analyses of genome-wide data with online-available tools
- design the algorithms for non-standard bioinformatics analyses of genomics data
- perform phylogenetic analysis using sequence information
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With the development of high-throughput genome-scale technologies, scientists get unprecedented access to data on the structure, function and evolution of genomes. In this course, we will overview the recent developments in genomics and train the bioinformatics tools and software used to gain insight in organismal physiology and evolution. We will start from the analysis of whole-genome datasets to identify the candidate genes for further bioinformatics analysis and to formulate testable hypothesis. Then we will screen the available genomics data to get new information about the candidate genes, e.g. where they express, with which conditions they associate, if their coding and non-coding regions possess any signals etc. Finally, we will perform phylogenetic analysis to understand evolution of the candidate genes and the evolutionary relationships of species. |
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| BSc level knowledge of molecular biology |
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| In-course assignments, exam |
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