After following this course, you can:
- easily navigate in genomics data; you know where and how to find the data you need
- get up-to-date information about genes of interest
- perform standard bioinformatics analyses of genome-wide data with online-available tools
- design the algorithms for non-standard bioinformatics analyses of genomics data
- perform phylogenetic analysis using sequence information
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With the development of high-throughput genome-scale technologies, scientists get unprecedented access to data on the structure, function, and evolution of genomes. In this course, we will overview the recent developments in genomics and train the bioinformatics tools and software used to gain insight into organismal physiology and evolution. In the "structural genomics" block, we will find, align, compare, and analyze DNA and protein sequences to solve biological problems. In the "comparative genomics" block, you will perform phylogenetic analysis to understand the evolution of the candidate genes and the evolutionary relationships of species. Finally, we will screen the available "functional genomics" data to get new information about the candidate genes, e.g., where they express, with which conditions they associate, if their coding and non-coding regions possess any signals, etc.
Instructional modes
- Lecture
- Tutorial
- Project
- Assignment
- Self-study
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BSc end-level knowledge of molecular biology. No programming skills are required.
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In-course assignments (20%), project (40%), exam (40%)
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