NWI-MOL038
Genetics
Course infoSchedule
Course moduleNWI-MOL038
Credits (ECTS)3
CategoryBA (Bachelor)
Language of instructionEnglish
Offered byRadboud University; Faculty of Science; Moleculaire Wetenschappen;
Lecturer(s)
Lecturer
dr. H. Huber
Other course modules lecturer
Examiner
dr. J.L. Peters
Other course modules lecturer
Lecturer
dr. J.L. Peters
Other course modules lecturer
Coordinator
dr. J.L. Peters
Other course modules lecturer
Contactperson for the course
dr. J.L. Peters
Other course modules lecturer
Academic year2018
Period
KW2  (05/11/2018 to 27/01/2019)
Starting block
KW2
Course mode
full-time
Remarks-
Registration using OSIRISYes
Course open to students from other facultiesYes
Pre-registrationNo
Waiting listNo
Placement procedure-
Aims
After this course you will be able to:
  • Identify and solve genetic problems, so that in future you will be able to understand scientific articles with a genetic background
  • Recognize the molecular background of a number of human genetic disorders and to perform human pedigree analysis
  • Calculate distances between genes and/or molecular markers and make genetic maps
  • Solve population genetic and quantitative genetic problems
  • Mention genetic techniques and clarity their importance in assigning functions to genes/sequences
  • Search public databases on the internet for information on the mutants and molecular markers you need during the practical laboratory course
  • Design experiments to identify the chromosomal location of genes responsible for two given mutations by map-based cloning
  • Present your experiments in the form of a report written in the format of a scientific article
Content
The theoretical part of the course includes the following subjects:
  • Meiosis and Mendelian genetics
  • Autosomal, sex-linked and cytoplasmatic inheritance patterns
  • Gene linkage en recombination
  • Gene interactions
  • Gene regulation in bacteria: LAC operon
  • Gene regulation in eukaruotes
  • Genomes & Genomics
  • Genetic mutations en polymorfisms
  • (Use of) molecular markers
  • Large-scale chromosomal changes
  • Population genetics
  • Quantitative genetics
During the obligatory 'dry' laboratory classes, the students will investigate on which chromosomes the genes responsible for two different mutations are located. To obtain the results the students will phenotype plants and analyse gel pictures. The results will be presented in a research report.
Test information
Written exam.
Lab classes are mandatory, and are concluded with a report. By accomplishing extra tasks one can obtain bonus points for the exam, but these cannot be used to compensate for a fail of the exam.

Prerequisites
At the start of the course all students test their level of Mendelian genetics. Depending on their performance they can follow remedial classes or make optional assignments to earn bonus points.This is a course in the programme 'Molecular life sciences'.

Required materials
Book
An Introduction to Genetic Analysis, 11th edition, Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley
ISBN:978-1-4641-0948-5
Course guide
Manual for practical course via Blackboard

Instructional modes
Lab course
Attendance MandatoryYes

Lecture

Response course
Attendance MandatoryYes

Tutorial

Zelfstudie

Tests
Exam
Test weight3
Test typeExam
OpportunitiesBlock KW2, Block KW3

Report
Test weight1
Test typeReport
OpportunitiesBlock KW2