NWI-MOL066
Structure, Function and Bioinformatics
Course infoSchedule
Course moduleNWI-MOL066
Credits (ECTS)6
CategoryBA (Bachelor)
Language of instructionDutch
Offered byRadboud University; Faculty of Science; Moleculaire Wetenschappen;
Lecturer(s)
Coordinator
dr. H. Venselaar
Other course modules lecturer
Contactperson for the course
dr. H. Venselaar
Other course modules lecturer
Lecturer
prof. dr. G. Vriend
Other course modules lecturer
Academic year2017
Period
KW3  (05/02/2018 to 15/04/2018)
Starting block
KW3
Course mode
full-time
Remarks-
Registration using OSIRISYes
Course open to students from other facultiesYes
Pre-registrationNo
Waiting listNo
Placement procedure-
Aims

At the end of the course, the student is capable of solving simple problems related to the macromolecular structure of a biomolecule
The student is capable of analyzing protein and nucleic acid structures using a molecular visualization program and by (web-based) computational techniques.
The student is capable of formulating and understanding structure-function relationships of biolmolecules and can apply such knowledge to the understanding of biological/medical problems.

Content

The first part of the course introduces detailed aspects of biomolecular structures. Subsequently, structural aspects of important biomolecular processes, such as transcription, trans-membrane signal transduction, transport and mobility, will be discussed. During the second half the details will be placed in a broader framework by studying bioinformatics methods (molecular dynamics, machine learning, homology modelling, force field methods, etc), but at all times with an eye at application of the techniques to design or analyse biomedical topics.

Literature

• Handouts during the course.
• Website

Teaching formats

• 40 hours guided group project work
• 100 hours computer course
• 12 hours lecture
• 6 hours question session
• 10 hours individual study period

Additional comments
This course will be taught in Dutch. There are 18 places available. Registration 1 month in advance.

Test information
Between exams, written final exam and reports of contracts. Active participation and participation are taken into account in the assessment.

Prerequisites
Bioinformatica (NWI-MOL029) or Bioinformatica A (NWI-MOL075)This is a course in the theme 'Methods'.

Required materials
Handouts
Handouts during the course
Blackboard
Website

Instructional modes
Lecture

Practical computer training

Project

Response course

Tests
Tentamen
Test weight1
OpportunitiesBlock KW3, Block KW4