NWI-MOL075
Bioinformatics A
Course infoSchedule
Course moduleNWI-MOL075
Credits (ECTS)3
CategoryBA (Bachelor)
Language of instructionEnglish
Offered byRadboud University; Faculty of Science; Moleculaire Wetenschappen;
Lecturer(s)
Coordinator		dr. H. Venselaar
Other course modules lecturer
Examiner		dr. H. Venselaar
Other course modules lecturer
Lecturer		dr. H. Venselaar
Other course modules lecturer
Lecturer		dr. H. Venselaar
Other course modules lecturer
Contactperson for the course		dr. H. Venselaar
Other course modules lecturer
Academic year2018
Period
KW1  (03/09/2018 to 04/11/2018)
Starting block
KW1
Course mode
full-time
Remarks-
Registration using OSIRISYes
Course open to students from other facultiesYes
Pre-registrationNo
Waiting listNo
Placement procedure-
Aims

After this course the student is able to:

  • apply bioinformatics methods to biological, (bio)chemical and biomedical problems.
  • consult bioinformatic databases via the WWW.
  • analyse protein sequenties that were found, make a (multiple) sequence alignment from these and deduce properties of one protein from known properties of other proteins.
  • apply knowledge of special properties of amino acids and the way these determine properties of proteins to biological, (bio)chemical and biomedical problems.
  • predict the secundary structures of proteins and use these in solving questions related to protein sequence.
  • partake in the followup courses: Structure, Function, Bioinformatics (MOL066) (macromolecular structures), Comparative Genomics (MOL073) (genomics) and Chemical Discovery and Design (CMBI101B).
Content
  • Use of databases and database search software. Sound knowledge of amino acids, their physical and chemical properties, and the relation between these properties and the structure and function of the protein as a whole.
  • Understanding of the significance of the results of sequence comparisons.
  • Prediction of secundary structures and the use of this predicted secundary structure in solving questions related to protein sequence.
  • Use of multiple sequence alignment software and the interpretation if its results.
  • Use of detected sequence homologues, and (sequence) databases and software for information retrieval of as yet uncharcterised proteins.
Additional comments
This is the Bioinformatics inntroductory course. In this course the student will learn how to work with data, databases and data structures, How to perform efficient search actions, BLAST, the amino acids, and most important the relation between those amino acids and a protein's structure and function. The course will consists of seminars, response seminars and lots of practical work in which the students will apply their knowledge. The last weeks will consist of a group project.

Test information
Written mid-term exam, project report and a final exam.

Prerequisites
Biochemistry (NWI-MOL008A)
This is a course in the theme 'Methods'.

Required materials
Handouts
Materials will be handed out during the course.

Instructional modes
Lecture

Practical computer training

Project

Zelfstudie

Tests
Exam
Test weight1
Test typeExam
OpportunitiesBlock KW1, Block KW2

Group assignment
Test weight1
Test typeAssignment
OpportunitiesBlock KW1, Block KW2