NWI-MOL108
Magnetic Resonance in Chemistry
Course infoSchedule
Course moduleNWI-MOL108
Credits (ECTS)3
CategoryBA (Bachelor)
Language of instructionEnglish
Offered byRadboud University; Faculty of Science; Moleculaire Wetenschappen;
Lecturer(s)
Coordinator
dr. E.R.H. van Eck
Other course modules lecturer
Lecturer
dr. E.R.H. van Eck
Other course modules lecturer
Contactperson for the course
dr. E.R.H. van Eck
Other course modules lecturer
Examiner
dr. E.R.H. van Eck
Other course modules lecturer
Academic year2018
Period
KW3  (28/01/2019 to 07/04/2019)
Starting block
KW3
Course mode
full-time
Remarks-
Registration using OSIRISYes
Course open to students from other facultiesYes
Pre-registrationNo
Waiting listNo
Placement procedure-
Aims

After successfully completing the course you will:

  • know the roots of the theoretical background behind the magnetic resonance phenomenon
  • be familiar with a number of 1D and 2D NMR experiments relevant to synthetic chemistry labs
  • be able use 1D and 2D NMR spectra to elucidate molecular structures
  • have gained some basic understanding of NMR spectrometer operation.
Content

Magnetic resonance techniques have a broad range of application in chemistry, physics, life sciences, materials science and medicine. This  course covers the basics of magnetic resonance spectroscopy and will describe its applications relevant to the chemistry lab. First, the theoretical framework of magnetic resonance is covered in the lectures using the vector model. The chemical shift, J-coupling and multiplet structure is described. Spectral editing techniques and 2D NMR experiments that are used for structure elucidation in addition to dynamical effects such as chemical exchange will all help the student to use NMR as a tool in their future research.

Description:

  • Magnetisation and spin angular momentum
    • Rotating frame
  • T1 and T2 Relaxation
    • Bloch equations
  • Spectrometer operation and data processing
  • NMR interactions
    • Chemical shift
    • J-coupling
  • Decoupling and spectral editing techniques
  • 2D NMR (COSY, HSQC, NOESY)
  • Dynamical processes.
Test information
Written exam

Prerequisites
Chemical Analysis (NWI-MOL001), and Spectroscopic Techniques (NWI-MOL019).This is a course in the theme 'Methods'.

Required materials
Book
O.Zerbe and S.Jurt, Applied NMR Spectroscopy for Chemists and Life Scientists, Wiley
ISBN:9783527327744

Recommended materials
Book
J. Keeler, Understanding NMR Spectroscopy, Wiley 2nd ed
Book
P.J. Hore, Nuclear Magnetic Resonance, Oxford Chemistry Primer

Instructional modes
Course

Lecture

Tutorial

Tests
Tentamen
Test weight1
OpportunitiesBlock KW3, Block KW4