Biophysical chemistry, often referred to as biophysics or physical biology, deals with biomacromolecules and complexes. The sophisticated interplay between molecular forces and chemical energy make reactions in living cells work. The discipline is highly multidisciplinary and the principles and concepts are drawn from chemistry, physics and biology. The field has huge potential and is fundamental for many other fields. Molecular motors found in cells are an inspiration for nanotechnology. The biopolymers and membranes from which they are constructed are an inspiration for materials science. Recently there has been an explosion of beautiful new results of molecular motors, self-assembly, the influence of molecular crowding and compartmentalization, single-molecule manipulation and imaging that have revolutionized the field. This course aims to uncover some of the fundamental biophysical concepts that are used to model and understand these complicated processes. The course is meant for molecular sciences students with a keen interest in biological physics and quantitative biology.