- Properly name organic molecules (systematic and common nomenclature) and draw structures in different two and three-dimensional representations.
- Predict and categorize different configurations and conformations of molecules, both in linear and ring systems.
- Distinguish several basic reaction types (addition, elimination, nucleophilic substitution and electrophilic aromatic substitution) use this knowledge to predict reaction products, considering both regioselectivity and stereoselectivity.
- Understand mechanisms and factors that govern the courses and rates of chemical reactions both qualitatively and, for simple reactions, also quantitatively.
In this course, we will discuss the structure and reactivity of molecules. We start with an introduction of organic molecules: names, properties, stereochemistry, 3D structure, etc. After that, we will use these concepts to understand different classes of reactions: substitution, elimination, addition reactions and electrophilic substitution reactions. After this course, you are able to predict how molecules will react, which are the mot likely products formed and how you are able to manipulate reaction conditions to accelerate or suppress reactions.|
- Hybridisation in organic molecules
- Isomerism, stereochemistry, configurations and conformations
- Drawing of molecules and projections
- Electron delocalisation and (anti)aromaticity
- Mechanisms of addition, nucleophilic substitution (SN1/SN2), elimination (E1/E2) and electrophilic aromatic substitution (SEAr) reactions
- Rates of elementary reactions