NWI-MOL127
Biochemistry
Course infoSchedule
Course moduleNWI-MOL127
Credits (ECTS)6
CategoryPB (Propaedeutic)
Language of instructionEnglish
Offered byRadboud University; Faculty of Science; Moleculaire Wetenschappen;
Lecturer(s)
PreviousNext 1
Lecturer
prof. dr. A. Cambi
Other course modules lecturer
Examiner
dr. H.A. Heus
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Coordinator
dr. H.A. Heus
Other course modules lecturer
Contactperson for the course
dr. H.A. Heus
Other course modules lecturer
Lecturer
dr. H.A. Heus
Other course modules lecturer
Academic year2020
Period
KW1-KW2  (31/08/2020 to 24/01/2021)
Starting block
KW1
Course mode
full-time
Remarks-
Registration using OSIRISYes
Course open to students from other facultiesYes
Pre-registrationNo
Waiting listNo
Placement procedure-
Aims
  • Describe the basic structures of nucleic acids, proteins and lipids
  • Understand the physico-chemical properties of amino acids and nucleotides and correlate these to nucleic acid and protein function
  • Explain the mechanisms of DNA and RNA metabolism in living cells
  • Understand general concepts of enzyme catalysis, kinetics and inhibition
  • Explain the mechanism of protein synthesis and usage of the genetic code
  • Describe how molecules can move through biological membranes
  • Describe the pathways and mechanisms that living organisms use to harness molecular energy for maintaining metabolism
Content
Biochemistry is the scientific discipline that studies chemical reactions occurring in living cells. The aim of the course is to provide the student with a general insight in the primary roles and actions of biomolecules in the living cell from a molecular perspective. Starting with a general description of the main cellular matrices in life, bacteria, animals and plant cells, and the structures and properties of the basic molecules of life, nucleic acids, proteins and lipids and variants thereof, detailed insights will be given on the functional aspects, biochemical processes and interplay that constitute life. The course will provide a broad overview with focus on (phospo)lipids, membranes, enzymes, nucleic acid and protein synthesis and metabolism, and the energy flow in life. In addition, an introduction to the most important techniques used to characterize and understand the action of biomolecules will be given.

Instructional Modes
Level

Presumed foreknowledge

Test information
The final grade will be determined by: - a compulsory midterm exam (50%, minimum grade 5) (Q1, resit opportunity in Q2) - a compulsory final exam (50%, minimum grade 5.5) (Q2) The course is passed if the average grade is 5.5 or higher.
The midterm is scheduled at the end of the first quarter (October), with a resit opportunity at the end of quarter 2 (January). The final exam is scheduled in the exam week of quarter 2 in January A resit for the final exam is scheduled in quarter 3.
Required materials
Book
Nelson & Cox, Lehninger Principles of Biochemistry, 7th ed + Sapling+ module: https://www.macmillanihe.com/page/detail/lehninger-principles-of-biochemistry-david-l-nelson/?sf1=barcode&st1=9781319108243 Order the pack via the study associations Sigma or Leonardo.

Instructional modes
Lecture

Tutorial

Tests
Digital Exam
Test weight1
Test typeDigital exam with CIRRUS
OpportunitiesBlock KW2, Block KW3

Digital Midterm
Test weight1
Test typeDigital exam with CIRRUS
OpportunitiesBlock KW1, Block KW2