|
After this course the student is able to:
- apply bioinformatics methods to biological, (bio)chemical and biomedical problems.
- consult bioinformatic databases via the WWW.
- analyse protein sequenties that were found, make a (multiple) sequence alignment from these and deduce properties of one protein from known properties of other proteins.
- apply knowledge of special properties of amino acids and the way these determine properties of proteins to biological, (bio)chemical and biomedical problems.
- predict the secundary structures of proteins and use these in solving questions related to protein sequence.
- partake in the followup courses: Structure, Function, Bioinformatics (MOL066) (macromolecular structures), Comparative Genomics (MOL073) (genomics) and Chemical Discovery and Design (CMBI101B).
|
|
- Use of databases and database search software. Sound knowledge of amino acids, their physical and chemical properties, and the relation between these properties and the structure and function of the protein as a whole.
- Understanding of the significance of the results of sequence comparisons.
- Prediction of secundary structures and the use of this predicted secundary structure in solving questions related to protein sequence.
- Use of multiple sequence alignment software and the interpretation if its results.
- Use of detected sequence homologues, and (sequence) databases and software for information retrieval of as yet uncharcterised proteins.
|
|
|
|
|
|