NWI-MOL157
Physical Organic Chemistry
Course infoSchedule
Course moduleNWI-MOL157
Credits (ECTS)3
CategoryBA (Bachelor)
Language of instructionEnglish
Offered byRadboud University; Faculty of Science; Moleculaire Wetenschappen;
Lecturer(s)
Coordinator
prof. dr. W.T.S. Huck
Other course modules lecturer
Lecturer
prof. dr. W.T.S. Huck
Other course modules lecturer
Contactperson for the course
prof. dr. W.T.S. Huck
Other course modules lecturer
Examiner
prof. dr. W.T.S. Huck
Other course modules lecturer
Academic year2021
Period
KW4  (11/04/2022 to 31/08/2022)
Starting block
KW4
Course mode
full-time
Remarks-
Registration using OSIRISYes
Course open to students from other facultiesYes
Pre-registrationNo
Waiting listNo
Placement procedure-
Aims
Central theme of this course:   What determines the rate of a reaction?
Aim
The aim of this course is to familiarize you with principles of physical organic chemistry that govern the reactivity of molecules and their assemblies.
Context
Physical organic chemistry looks beyond the synthesis and structure of molecules to chemical reactions and the way both molecular structure and the chemical and physical environment impact on those reactions.  By understanding how the rates of chemical reactions can thus be altered, you will develop a deeper intuition into how reactions proceed, and how catalysts can accelerate reactions. Furthermore, the explicit link to ‘wet’ physical chemistry will serve as an excellent basis to explore other concepts in soft matter science, ranging from polymers and materials to living systems.
 
 
Using Atkins 11th Edition (see TOPICS) as general guide:
- Reaction limitations (= “classical” reaction kinetics = energy limitations): TOPIC 17A-F
- Equilibrium reactions, steady state approximation, consecutive reactions, rate determining steps, pre-equilibrium, enzyme catalysis
                - Transition-state theory TOPIC 18C
- Diffusion limitations (explain key concepts): TOPIC 18B and 16C
                - Fick’s law
                - Osmosis
                - Brownian motion
- Self-assembly TOPIC 14 (B+) E
                - general principles
                - colloids, micelles, bilayers, vesicles
 
Additional material (to be decided by lectures as ‘ special interest topics):
                - Catalyst, basic principles
                - Acid/base catalysis
                - Photochemistry
- Active motion: molecular motors and other active matter
               
 
Content
Central theme of this course:   What determines the rate of a reaction?
Aim
The aim of this course is to familiarize you with principles of physical organic chemistry that govern the reactivity of molecules and their assemblies.
Context
Physical organic chemistry looks beyond the synthesis and structure of molecules to chemical reactions and the way both molecular structure and the chemical and physical environment impact on those reactions.  By understanding how the rates of chemical reactions can thus be altered, you will develop a deeper intuition into how reactions proceed, and how catalysts can accelerate reactions. Furthermore, the explicit link to ‘wet’ physical chemistry will serve as an excellent basis to explore other concepts in soft matter science, ranging from polymers and materials to living systems.
 
 
Using Atkins 11th Edition (see TOPICS) as general guide:
- Reaction limitations (= “classical” reaction kinetics = energy limitations): TOPIC 17A-F
- Equilibrium reactions, steady state approximation, consecutive reactions, rate determining steps, pre-equilibrium, enzyme catalysis
                - Transition-state theory TOPIC 18C
- Diffusion limitations (explain key concepts): TOPIC 18B and 16C
                - Fick’s law
                - Osmosis
                - Brownian motion
- Self-assembly TOPIC 14 (B+) E
                - general principles
                - colloids, micelles, bilayers, vesicles
 
Additional material (to be decided by lectures as ‘ special interest topics):
                - Catalyst, basic principles
                - Acid/base catalysis
                - Photochemistry
- Active motion: molecular motors and other active matter
               


Instructional Modes
Level

Presumed foreknowledge

Test information
Exam (100%)
Specifics

Required materials
Book
Atkins' Physical Chemistry. 11th Edition

Instructional modes
Course
Attendance MandatoryYes

Tests
Exam
Test weight1
Test typeExam
OpportunitiesBlock KW4, Block KW4, Block KW4