NWI-MOL401
Chemical Biology
Course infoSchedule
Course moduleNWI-MOL401
Credits (ECTS)3
CategoryMA (Master)
Language of instructionEnglish
Offered byRadboud University; Faculty of Science; Moleculaire Wetenschappen;
Lecturer(s)
Coordinator
dr. T.J. Boltje
Other course modules lecturer
Examiner
dr. T.J. Boltje
Other course modules lecturer
Lecturer
dr. T.J. Boltje
Other course modules lecturer
Contactperson for the course
dr. T.J. Boltje
Other course modules lecturer
Lecturer
dr. K.M. Bonger
Other course modules lecturer
Academic year2019
Period
KW1  (02/09/2019 to 03/11/2019)
Starting block
KW1
Course mode
full-time
Remarks-
Registration using OSIRISYes
Course open to students from other facultiesYes
Pre-registrationNo
Waiting listNo
Placement procedure-
Aims
  • Understand how to introduce selective modifications and construct conjugates of biomolecules
  • Have a working knowledge of chemical genetics and chemical ligation
  • Know the concept of fusion proteins and their uses
  • Understand the principles of protein engineering, including the use of non-natural amino acids
Content
This course aims to provide a general overview of the core concepts of Chemical Biology. This is an interdisciplinary research area between chemistry and biology, where molecules and chemical techniques are used to study, monitor and influence biological systems. The student is provided with a broad overview on the chemical methods to modify bio-molecules, both in vivo and in vitro. We will discuss how cells can be influenced on the level of genetic, proteomic and metabolic level and how changes can be measured quantitatively using new developments in analytical tools as fluorescence and other microscopy-based techniques, mass spectrometry and NMR.
The aim of the course is to provide the student with an overview of the toolbox of chemical approaches used to unravel and influence molecular processes inside (living) cells.
Level

Presumed foreknowledge
This is a mandatory course in the specialisation 'Chemistry for Life'.
Test information
Written exam
Specifics

Test information
Written exam

Prerequisites
This is a mandatory course in the specialisation 'Chemistry for Life'.

Required materials
Handouts
Handouts distributed during the course.

Instructional modes
Lecture
Attendance MandatoryYes

Tutorial
Attendance MandatoryYes

Zelfstudie

Tests
Tentamen
Test weight1
Test typeExam
OpportunitiesBlock KW1, Block KW2