prof. dr. J.R. Homberg (Judith)

Hoofdonderzoeker - Donders Center of Medical Neurosciences
Hoofdonderzoeker - Donders Institute for Brain, Cognition and Behaviour
Hoogleraar - Faculteit der Medische Wetenschappen (Radboudumc)

prof. dr. J.R. Homberg (Judith)
Contactinformatie
Bezoekadres

Kapittelweg 29
6525 EN NIJMEGEN
Interne postcode: 205

Postadres

Postbus 9101
6500 HB NIJMEGEN

Our translational animal experimental research focuses on (serotonergic) genetic and environmental factors that influence brain development and behavioural traits. Interactions between these factors may lead to maladaptive emotional responses as seen in stress-related disorders and addiction, but also cognitive improvements, depending on environmental conditions. It is our overarching hypothesis that the cognitive improvements can be used to offset the maladaptive emotional responses. To test this hypothesis we use unique mutant rats that model human genetic polymorphisms, including the serotonin transporter knockout rat. We also investigate the role of serotonin and environmental factors in brain development and long-term effects on behaviour and cognition. Our main expertise is measuring basic and complex (translational) behaviours in rats, which we combine with invasive measurements, pharmacological manipulations, in vivo neurochemical measurements and neuroimaging, molecular genetic analyses, and immunohistochemical assessments.

Onderzoeksthema Onderzoeksgroep

Publicaties

Onderzoeksbeurzen en -prijzen

Projecten

Onderwijs

Curriculum Vitae

Over
Judith Homberg onderzoekt factoren die invloed hebben op de ontwikkeling van het brein en gedragskenmerken. Interacties hiertussen kunnen leiden tot emotionele reacties. Ze verwacht dat interventies die ontwikkeling stimuleren deze reacties kunnen compenseren.