dr. ir. M.M. Verbeek (Marcel)
Principal Investigator - Donders Center of Medical Neurosciences
Principal Investigator - Donders Institute for Brain, Cognition and Behaviour
My research is focused on the neurochemistry of neurodegenerative disorders, specifically movement disorders (e.g. Parkinson’s disease) and dementia syndromes (in particular cerebral amyloid angiopathy, Alzheimer’s disease). I study the development and validation of biomarkers in body fluids (especially cerebrospinal fluid) for diagnosis and prognosis of these disorders; I collaborate with the Parkinson Centre Nijmegen and the Radboud Alzheimer Centre as well as with many (inter)national researchers. I also study pathophysiological mechanisms of cerebrovascular amyloid formation focusing on aggregation of disease-related proteins, interaction with other proteins and cerebral cells and clearance pathways of these proteins from the brain.
- 2014 - 2018 ZonMW- Memorabel Programma. “CAVIA: Cerebral Amyloid Angiopathy: Vascular Imaging and fluid markers of Amyloid deposition”. A study on the identification of novel biomarkers for CAA. Meer informatie
- 2015 - 2018 Aβ clearance and barrier dysfunction in CAA (Alzheimer Nederland)
- 2016 - 2019 BrainMatTrain (ITN- Marie Skłodowska-Curie)
- 2018 - 2022 BIONIC: BIOmarkers for cogNitive Impairment due to Cerebral Amyloid Angiopathy (ZonMW- Memorabel Programma)