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Research facilities

To study the complex neural networks underlying perceptual, motor and cognitive brain functions in ever greater detail, the Donders Centre for Neuroscience (DCN) has several state-of-the-art facilities, and is taking the lead in developing and implementing new techniques.

PRIME

prime1

At the pre-clinical imaging facility (PRIME) of the CDL a two-photon imaging set-up is available that can be combined with behaviour and neurophysiology. The set-up consists of a Leica TCS SP5 and Chameleon Ultra II Laser system with a resonance scanner (@512x512 30 Hz).

Drosophila facilities

Vliegenlab 2019-153827

The Drosophila facilities contain all necessary equipment for fly genetics, including 8 stereomicroscopes, fly pads, and 4 incubators. In addition, equipment to monitor Drosophila motor performance (automated negative geotaxis assay) is available, and the rooms are temperature- and light-controlled, to allow for state-of-the-art Drosophila behavioral analysis.

Translational Neuroscience Unit (TNU)

TNU lab foto

At the Translational Neurocscience Unit (TNU) in the CDL multiple behavioural set-ups are available as well as stereotaxic surgery and wet-lab facilities. Within the TNU we share expertise in behaviour, phenotyping, electrophysiology and molecular approaches.

Vestibular chair

vestibular chair

With this unique vestibular stimulator it is possible to rotate the subjects around two independent computer-controlled axles, while performing cognitive or motoric tasks. While the subject is being rotated, the stimulator offers visual and aural stimuli. (more information)

Neuroimaging Facilities

imaging-neuroscience

Our researchers have access to neuroimaging facilities such as Magnetic Resonance Imaging (MRI) at 1.5, 3 and 7 Tesla, Magnetoencephalography (MEG), Electroencephalography (EEG) and Transcranial Magnetic Stimulation (TMS) which make it possible to look inside the skull - in a variety of ways.

NIRS-EEG

NIRS EEG

With this measuring instrument it is possible to measure brain activity with a high temporal resolution (EEG) in combination with a reasonable (sub-cm) spatial resolution (NIRS). (more information)

Mobile auditory lab

mobiele_auditieve_lab_2

The facility consists of two mobile eye-tracking systems that may be or may not be used in combination in a virtual acoustic environment. One of the systems is specially designed for children. (more information)

Neurohistology Unit

Neurohistology Unit1

In the Neurohistology Unit all histological approaches (including cryosectioning) can be performed to explore the fascinating morphological features of nervous tissue. The Neurohistology Unit is closely coupled to the state-of-the-art microscopy facility of the General Instrumentarium (from widefield to Lightsheet microscopy) and the Neuro Culture Lab.